CClinicalTrials.gg
CompletedNCT05461989Updated Sep 22, 2025

Physical Activity Barriers in Adolescent Hypertension Patients

An observational study in Physical Inactivity, sponsored by Hacettepe University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 10 Years to 19 Years. Per ClinicalTrials.gov, last updated 2025-09-22.

Sponsored by Hacettepe University · Observational

Study type
Observational
Model
Case-control
Time perspective
Cross-sectional
Enrollment
66
Ages
10 Years to 19 Years
Sex
All
01

Study summary

One of the most prevalent chronic disorders in children, especially teenagers, is hypertension . The prevalence of hypertension has significantly increased in recent years, particularly with the rise in obesity. It has been demonstrated that hypertension is a significant, controllable risk factor for cardiovascular disease and that it is linked to atherosclerosis in children. Additionally, in patients with hypertension who were monitored from infancy to adulthood, it was discovered that the unfavorable cardiac alterations and vascular damage linked to hypertension were linked to early cardiovascular disease in adults. Therefore, the key to preventing cardiovascular disease in children and adolescents-especially when risk factors like obesity, diabetes, or chronic renal disease are present-is early diagnosis and effective treatment of hypertension. Insufficient exercise and sedentary lifestyles are additional risk factors for pediatric hypertension.Investigating physical activity barrier in teenage hypertension patients is vital in light of all these factors as well as studies on adolescents' inadequate physical activity. The literature is lacking studies examining the obstacles to physical exercise faced by people with adolescent hypertension, hence this topic is open for investigation.

Read the detailed description

One of the most prevalent chronic disorders in children, especially teenagers, is hypertension . The prevalence of hypertension has significantly increased in recent years, particularly with the rise in obesity . Primary hypertension, also known as essential hypertension, which was once thought to be an adult condition, is becoming more prevalent in the pediatric population, partly because of the obesity pandemic . Children who are obese have a three times higher risk of developing hypertension than children who are not obese . Based on the etiology, hypertension can be divided into two types: primary or essential hypertension, which has no known cause, and secondary hypertension, which has a known cause. Stage I (mild) hypertension is the most common symptom of primary hypertension, which is also linked to a favorable family history . Very young children, those with stage II hypertension, and those with clinical signs suggesting systemic disorders linked to hypertension should all be evaluated for secondary hypertension. An underlying vascular, neurological, endocrine, or renal parenchymal illness may cause secondary hypertension .

It has been demonstrated that hypertension is a significant, controllable risk factor for cardiovascular disease and that it is linked to atherosclerosis in children. Additionally, in patients with hypertension who were monitored from infancy to adulthood, it was discovered that the unfavorable cardiac alterations and vascular damage linked to hypertension were linked to early cardiovascular disease in adults.Therefore, the key to preventing cardiovascular disease in children and adolescents-especially when risk factors like obesity, diabetes, or chronic renal disease are present-is early diagnosis and effective treatment of hypertension.

Insufficient exercise and sedentary lifestyles are additional risk factors for pediatric hypertension. Low levels of physical activity and hypertension have a continuous, temporal, and independent association, according to epidemiological research . According to data, 80% of kids and teenagers in 105 countries do not engage in the recommended amount of physical exercise, which is at least 60 minutes of moderate to strenuous activity per day.Additionally, many kids and teenagers engage in sedentary activities for more than 4 hours per day, even though less than 2 hours per day are advised for screen-based entertainment (such as watching TV, using a computer, and playing video games). According to research, children and adolescents who watch television or spend too much time on screens had lower fitness levels, worse self-esteem, less prosocial behavior, and higher systolic and diastolic blood pressure. Prospective research regularly demonstrates that exercise shields adults from high blood pressure. Physical activity has been dubbed a "poly-drug" for its preventive and therapeutic effects in reducing the global health burden of cardiovascular disease, increasing physiological function, and slowing cardiovascular aging.Investigating physical activity barrier in teenage hypertension patients is vital in light of all these factors as well as studies on adolescents' inadequate physical activity. The literature is lacking studies examining the obstacles to physical exercise faced by people with adolescent hypertension, hence this topic is open for investigation.

02

Conditions studied

  • Physical Inactivity

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03

In context

Sedentary Behavior

332 studies on the registry are indexed under Sedentary Behavior; 155 are open to participants now.

This study's enrollment of 66 is below the median of 157 across 44 observational studies indexed under Sedentary Behavior.

Browse Sedentary Behavior studies →

Lead sponsor

Hacettepe University is the lead sponsor of 983 studies on the registry; 212 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
10 Years to 19 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

adolescent primary and secondary hypertension patients

Eligibility criteria

For Primary Hypertension

Inclusion Criteria:

  • Being 10-19 years old,
  • Being diagnosed with primary hypertension,
  • Being clinically stable and no drug/drug dose changes for the last four weeks,
  • Determined to be voluntary to participate in the study

Exclusion Criteria:

  • Having a neurological, cognitive or orthopedic disease that will affect the measurements,
  • Severe respiratory system disease (FEV1 \<35%; FVC \<50%),
  • Having acute infection,
  • Having malignancy,
  • Receiving hormone replacement therapy,
  • Body mass index >40 kg/m²,
  • Ejection fraction less than 50%,
  • Having uncontrolled hypertension,
  • Individuals with diabetes will not be included in the study.

For Secondary Hypertension

Inclusion Criteria:

  • Being 10-19 years old,
  • Being diagnosed with secondary hypertension,
  • Being clinically stable and no drug/drug dose changes for the last four weeks,
  • Not being under high-dose glucocorticoid therapy (2 mg/kg/day),
  • Not taking intravenous biologic or conventional immunosuppressive therapy (including pulsed steroids) in the past month
  • Determined to be voluntary to participate in the study

Exclusion Criteria:

  • Having a neurological, cognitive or orthopedic disease that will affect the measurements,
  • Severe respiratory system disease (FEV1 \<35%; FVC \<50%),
  • Having acute infection,
  • Having malignancy,
  • Receiving hormone replacement therapy,
  • Body mass index >40 kg/m²,
  • Ejection fraction less than 50%,
  • Having uncontrolled hypertension,
  • Individuals with diabetes will not be included in the study.
05

Study design

Observational model
Case-control
Time perspective
Cross-sectional
Enrollment
66 participants (actual)
Target follow-up
12 Months
Patient registry
Yes

Groups and cohorts

  • primary hypertension

    adolesence primary hypertension patients

    Other: Anthropometric measurement · Other: Level of Physical Activity · Other: Physical Activity Barriers Scale · Other: Hand Grip Strength · Other: Arterial stiffness

  • secondary hypertension

    adolesence secondary hypertension patients

    Other: Anthropometric measurement · Other: Level of Physical Activity · Other: Physical Activity Barriers Scale · Other: Hand Grip Strength · Other: Arterial stiffness

Interventions

  • OtherAnthropometric measurement

    It will be measured with the Xiaomi Body Composition Scale II, and a total of 9 measurements will be made as a result of the measurements.

  • OtherLevel of Physical Activity

    The scale to be used for this purpose is the Child Physical Activity Questionnaire (CPAQ) developed by Kowalski et al. It is a seven-day self-reported recall scale designed to assess moderate-intensity physical activity in children aged 8-14 years. CFAQ is designed to be implemented throughout the school year.

  • OtherPhysical Activity Barriers Scale

    It consists of three surveys in total, which are: A) Scale of Expectations Regarding Physical Activity for Children B) Children's perception of family support regarding physical activity scale C) Physical Activity Barriers Scale for Parents

  • OtherHand Grip Strength

    Hand grip strength will be measured using a hand dynamometer (Jamar, Sammons Preston, Rolyon, Bolingbrook, IL).

  • OtherArterial stiffness

    Arterial stiffness will be evaluated using the pulse wave velocity (PWV) technique with the blood pressure holter-ABPM (Mobil-O-Graph, I.E.M., Stolberg, Germany) device. The measurement is made from the non-dominant arm based on the principle of blood pressure measurement with the appropriate cuff determined according to the arm diameter. After two consecutive measurements taken 30 seconds apart, the average of the measurement values will be recorded.

06

What researchers measure

Primary outcomes

  1. physical activity barriers

    With a scale consisting of three questionnaires in total (Parent Physical Activity Barriers scale, the Child Physical Activity Outcome Expectancies Scale, and the Child Physical Activity Home Environment scale), the barriers of individuals to physical activity will be evaluated. As a result of these evaluations, it will guide us to understand the causes of physical activity barriers in primary and secondary hypertension patients.

    Time frame: 12 months

07

Study locations

1 site
  • Hacettepe University
    Ankara, Turkey (Türkiye)
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 22, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05461989
Lead sponsor
Hacettepe University
Responsible party
E.Burcu ÖZCAN (Physiotherapist (MSc), Hacettepe University) — Principal investigator
First posted
Jul 18, 2022
Start date
Sep 30, 2022
Primary completion
Mar 30, 2024
Completion
Sep 1, 2024
Last update
Sep 22, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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