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CompletedNCT05409469Updated Jun 8, 2022

Clinical Characteristics, Management Patterns and Outcomes of Type A Aortic Dissection: A Sino-US Comparative Cohort Analysis

An observational study in Aortic Dissection, sponsored by Xin Chen. Completed. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2022-06-08.

Sponsored by Xin Chen · Observational

Study type
Observational
Model
Cohort
Time perspective
Other
Enrollment
11,550
Ages
18 Years and older
Sex
All
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Study summary

This study constructed a retrospective cohort study by retrospectively analyzing the data of all patients with aortic dissection from January 1, 2012 to December 31, 2021 from the Cardiovascular Disease Registration System of Jiangsu Province in China and the data of similar diseases in recent years from National Inpatient Sample database in the United States

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Conditions studied

  • Aortic Dissection

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Keywords

  • Aortic Dissection
  • China
  • the United States
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In context

Aortic Dissection

386 studies on the registry are indexed under Aortic Dissection; 117 are open to participants now.

This study's enrollment of 11,550 is above the median of 183 across 180 observational studies indexed under Aortic Dissection.

Browse Aortic Dissection studies →

Lead sponsor

Xin Chen is the lead sponsor of 4 studies on the registry; 1 is open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

All patients with aortic dissection in Jiangsu Aortic Registry system of China from January 2012 to December 2021 and all patients with aortic dissection in National Inpatient Sample database of the United States from January 2015 to December 2019.

Inclusion criteria

1.Clinical diagnosis of type A Aortic Dissection

Exclusion criteria

Exclusion Criteria:

  1. age\<18, age unknown,
  2. diagnosis of aortic aneurysm, transfer out within 1 day,
  3. unknown vital status at discharge;
  4. unknown treatment type: cardioplegia, valve or cardiac repair only without aortic repair or two types of treatments on different days
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Study design

Observational model
Cohort
Time perspective
Other
Enrollment
11,550 participants (actual)
Target follow-up
5 Years
Patient registry
Yes

Groups and cohorts

  • Chinese patients with aortic dissection

    Clinical characteristics, management patterns and outcomes of type A aortic dissection in China.

    Procedure: surgery

  • American patients with aortic dissection

    Clinical characteristics, management patterns and outcomes of type A aortic dissection in the United States.

    Procedure: surgery

Interventions

  • Proceduresurgery

    surgery on patients with aortic dissection

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What researchers measure

Primary outcomes

  1. Baseline data of patients with type A aortic dissection was assessed by SPSS 17.0

    Baseline data of patients with type A aortic dissection included gender, age,height, weight, past medical history, family history, hospital costs, etc.

    Time frame: from 2015 to 2019

  2. The main efficacy indicators was assessed by SPSS 17.0.

    The main efficacy indicators included surgical procedures, surgical outcome (postoperative bleeding, ICU stay, extubation time), perioperative complications (including infection, bleeding, neurological complications, cardic complications, renal insufficiency, etc.), and postoperative mortality.

    Time frame: from 2015 to 2019

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Study locations

No study locations are listed for this record.

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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 8, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05409469
Lead sponsor
Xin Chen
Collaborators
China Medical University, China
Responsible party
Xin Chen (Clinical Professor, Nanjing First Hospital, Nanjing Medical University) — Sponsor-investigator
First posted
Jun 8, 2022
Start date
Jan 2012
Primary completion
Dec 2021
Completion
Dec 2021
Last update
Jun 8, 2022

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2022. You cannot join it, but the record below documents what was studied.

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