An interventional study of root canal filling with Ceraseal sealer in Endodontically Treated Teeth, sponsored by University of Bologna. Completed at 1 site in Italy. Open to participants aged 18 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-05-17.
Sponsored by University of Bologna · Not applicable, Interventional, and Treatment
The clinical use of a flowable premixed calcium-silicate bioceramic sealer used in association with warm carrier-based/single-cone technique will be compared with epoxy resin-based sealer with carrier-based technique.
Healthy consecutive patients (n= 109) requiring 141 root canal treatments were enrolled in this study and divided in 3 groups (Group 1: Ceraseal + single cone cold technique n=47. Group 2: Ceraseal + Carrier-based technique n=47. Group 3 AH Plus + Carrier based technique n=47).
Periapical X-rays were taken preoperatively, after root canal filling and after 6, 12 and 24 months. Two evaluators blindly assessed the Periapical Index (PAI) and sealer extrusion in the 3 groups (k =0.90). Healing rate and survival rate were also analysed.
Chi square tests was used to analyse significant differences among the groups. Multilevel analysis was performed to analyse the factors associated to healing status and survival status.
118 studies on the registry are indexed under Tooth, Nonvital; 18 are open to participants now.
This study's enrollment of 109 is above the median of 50 across 108 interventional studies indexed under Tooth, Nonvital.
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Exclusion Criteria:
Premixed flowable hydraulic calcium silicate sealer was applied with a a K File #15 that was inserted into the canal to reach the WL - 3mm and gently moved around the root canal walls. Then, gutta-percha points were gently inserted at the WL -0.5mm and compacted with lateral condensation/vertical condensation.
Other: root canal filling with Ceraseal sealer
Premixed bioceramic sealer was applied and previously described. Pre-heated carrier was inserted in the canal at WL-0.5mm. The carrier excess was removed with a Thermacut bur.
Other: root canal filling with Ceraseal sealer
Epoxy-resin-based sealer was mixed and immediately inserted into the root canal using a K File #15. Pre-heated carrier was inserted in the canal at WL -0.5mm. The carriers excess was removed with a bur.
Other: root canal filling with Ceraseal sealer
root canal filling with Ceraseal sealer
Healing rate
Periapical index minor than 3 at the endline
Time frame: 24 months
Survival rate
presence of root canal treated tooth at the endline
Time frame: 24 months
Plan to share: No
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This study is completed, as verified in May 2022. You cannot join it, but the record below documents what was studied.
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