An interventional study of DANE Recovery Program and Questionnaires in Delirium, sponsored by University of Wisconsin, Madison. Active, not recruiting at 6 sites in United States. Open to participants aged 65 Years and older. Per ClinicalTrials.gov, last updated 2026-07-07.
Sponsored by University of Wisconsin, Madison · Not applicable, Interventional, and Treatment
This study will evaluate the usefulness of the Urgent and Emergency Surgery (UES) Delirium Recovery Model. It is hypothesized that the cognitive, physical and psychological recovery of older UES delirium survivors will be improved through the use of the DANE Recovery Model. Participants can expect to be on the study for 18 months.
This is a multi-site, two-arm, single-blinded randomized controlled clinical trial to evaluate the efficacy of the DANE Recovery Model to improve the cognitive, physical and psychological recovery of older UES delirium survivors. At or near the time of discharge, enrolled participants will be randomized to receive the DANE Recovery Model or usual care. The hypothesis is that, after 18 months, older UES delirium survivors who are randomized to the DANE Recovery Model will experience more favorable cognitive, physical and psychological recovery in comparison to those randomized to usual care.
1,058 studies on the registry are indexed under Delirium; 238 are open to participants now.
This study's planned enrollment of 528 is above the median of 120 across 599 interventional studies indexed under Delirium.
Browse Delirium studies →University of Wisconsin, Madison is the lead sponsor of 1,161 studies on the registry; 182 are open to participants now.
Of its 151 completed or terminated interventional studies of FDA-regulated products, 114 (75%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
The delivery of the model will occur in five phases that correspond to the known stages of recovery after surgery. During the acute stage (0 - 1 month after surgery), participants will undergo the initial case review and two initial virtual visits, and the development of the recovery care plan. During the recovery (2 - 6 months after surgery) and maintenance (7-12 months after surgery) stages, the participants will undergo the interaction phase of the DANE Recovery Model.
Other: DANE Recovery Program
Participants will receive the usual rehabilitation and post-operative care.
Other: DANE Recovery Program · Other: Questionnaires
Virtual visits with care coordinator to carry out an individualized recovery plan
Physical, cognitive, and psychological assessments
Change in overall cognitive recovery
Change in score on the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) cognitive screening assessment. The measure consists of 12 subtests that contribute to a total score and Index scores across five domains: Immediate Memory, Visuospatial-Constructional, Language, Attention, and Delayed Memory. Index scores are converted to age-based standard scores (Mean = 100, Standard Deviation = 15)
Time frame: Baseline, 6 months, 12 months, and 18 months
Short Physical Performance Battery (SPPB)
Change in overall physical recovery will be assessed using Short Physical Performance Battery (SPPB). SPPB is a group of measures that combines the results of the gait speed, chair stand and balance tests, and yields a performance score of 0-12; 0-4 poor, 5-7 intermediate, 8-12 good.
Time frame: Baseline, 6 months, 12 months, and 18 months
Change in overall physical recovery
Change in overall physical recovery will be assessed using 36-Item Short Form Survey (SF-36). SF-36 scale has eight components (physical functioning, role-physical, bodily pain, general health, vitality, social functioning, role-emotional, and mental health).
Time frame: Baseline, 6 months, 12 months, and 18 months
Patient Health Questionnaire-9 (PHQ-9)
Change in overall psychological recovery will be assessed using Patient Health Questionnaire-9 (PHQ-9). The PHQ-9 is a nine-item depression scale with a total score from 0 to 27, with higher scores indicating greater depression.
Time frame: Baseline, 6 months, 12 months, and 18 months
General Anxiety Disorder-7 (GAD-7) .
Change in overall psychological recovery will be assessed using General Anxiety Disorder-7 (GAD-7) to determine the impact of the intervention on participant's mood and anxiety. The GAD-7 is a seven-item anxiety scale with a total score from 0 to 27, with higher scores indicating greater anxiety.
Time frame: Baseline, 6 months, 12 months, and 18 months
Documents are hosted by the registry — open the source record to download them.
Plan to share: No
This study is active, not recruiting, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.
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University of Wisconsin, Madison