An interventional study of tai ji quan and Stretching in Mild Cognitive Impairment, sponsored by Oregon Research Institute. Completed at 1 site in United States. Open to participants aged 65 Years to 95 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-03-22.
Sponsored by Oregon Research Institute · Not applicable, Interventional, and Prevention
This project is designed to develop and evaluate an Internet-based exercise intervention (tai ji quan Moving to Improve Brain Health) using real-time videoconferencing for older adults with mild cognitive impairment (MCI).
The project has three major goals: (a) transforming an in-person tai ji quan brain health intervention protocol into an online (virtual) class protocol and evaluating its feasibility of implementation in older adults with MCI, (b) developing and evaluating online assessment and data ascertainment procedures that encompass cognitive and physical performance measures, and (c) conducting a randomized controlled trial comparing the effectiveness of this new online intervention protocol with a conventional stretching exercise group in older adults with MCI.
3,843 studies on the registry are indexed under Cognitive Dysfunction; 1,100 are open to participants now.
This study's enrollment of 69 is close to the median of 65 across 2,808 interventional studies indexed under Cognitive Dysfunction.
Browse Cognitive Dysfunction studies →Oregon Research Institute is the lead sponsor of 70 studies on the registry; 5 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion criteria:
Participants receive a cognitively enhanced tai ji quan exercise intervention for 16 weeks.
Behavioral: tai ji quan
Participants receive a stretching exercise intervention for 16 weeks.
Behavioral: Stretching
cognitively enhanced tai ji quan exercise
Stretching exercise
(a) Total number of intervention sessions taught by instructors over the course of study (recorded by a class check sheet) and (b) total number of classes attended by participants over the course of intervention as recorded by class attendance sheet
assess the extent to which interventionists successfully implement the prespecified exercise training protocol.
Time frame: 16 weeks
number of dropouts from the intervention and study as assessed by a study recording sheet
assess intervention dropout rate and retention rate
Time frame: 16 weeks
Number of participants expressing intervention program satisfaction as assessed by a self-report survey
assess the program acceptability among tai ji quan participants
Time frame: 16 weeks
Change in global cognitive function assessed by Montreal Cognitive Assessment
assess change from baseline cognitive function at 16 weeks
Time frame: baseline, 16 weeks
Change in attention and working memory as assessed by Digit Span - forward and backward
assess change from baseline in attention and working memory at 16 weeks
Time frame: baseline, 16 weeks
Change in dual-task cost as assessed by Timed Up and Go with a cognitive task
assess change from baseline in the ability to stand up from a chair, walk, and sit down while performing an arithmetic task at 16 weeks
Time frame: baseline, 16 weeks
Change in executive function as assessed by Trail Making B
assess change from baseline executive function at 16 weeks
Time frame: baseline, 16 weeks
Change in executive function as assessed by Category Fluency for Animals
assess change from baseline executive function at 16 weeks
Time frame: baseline, 16 weeks
Change in cognitive functioning assessed by Everyday Cognition
assess change from baseline cognitive functioning at 16 weeks
Time frame: baseline, 16 weeks
Change in physical performance as measured by Timed Up and Go test
assess change from baseline in the ability to stand up from a chair, walk, and sit down at 16 weeks
Time frame: baseline, 16 weeks
change in leg strength as assessed by 30-second chair stand test
assess change from baseline in leg strength at 16 weeks
Time frame: baseline, 16 weeks
Change in balance using a 4-stage balance test
assess change from baseline in balance at 16 weeks
Time frame: baseline, 16 weeks
Change in depression as assessed by Geriatric Depression scale
assess change from baseline in the level of depression at 16 weeks
Time frame: baseline, 16 weeks
Change in physical activity as assessed by International Physical Activity Questionnaire
assess change from baseline in physical activity at 16 weeks
Time frame: baseline, 16 weeks
Change in quality of life as assessed by EuroQol (EQ-5D-3L)
assess change from baseline in quality of life at 16 weeks
Time frame: baseline, 16 weeks
Plan to share: Yes — There is a plan to make IPD and related data dictionaries available.
Supporting information: Study protocol
No publications or documents are linked to this record.
This study is completed, as verified in Mar 2023. You cannot join it, but the record below documents what was studied.
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Oregon Research Institute