An interventional study of Rehabilitation in Nocturnal Enuresis, sponsored by University of Alexandria. Status unknown at 1 site in Egypt. Open to participants aged 5 Years to 30 Years. Per ClinicalTrials.gov, last updated 2023-01-12.
Sponsored by University of Alexandria · Not applicable, Interventional, and Treatment
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Among 22 studies in Nocturnal Enuresis with a site in Egypt — 5 open to participants now, 7 under way, 2 of them phase 3. Nocturnal Enuresis · Egypt.
Among the 22 studies in Nocturnal Enuresis with a site in Egypt, this one is the 18th largest by planned enrollment of the 18 interventional ones that give a count, is one of 3 that started in 2023, is one of 13 with no phase, and was the 5th registered.
105 studies on the registry are indexed under Nocturnal Enuresis; 22 are open to participants now.
Browse Nocturnal Enuresis studies →5 of the 22 studies in Nocturnal Enuresis with a site in Egypt are open now. Recruiting first, the newest first:
Al-Azhar University · Sites in Egypt
Ages 6–14
Mansoura University · Sites in Egypt
Ages 6–18
Al-Azhar University · Sites in Egypt
Ages 7–14
Benha University · Sites in Egypt
Ages 5–15
Cairo University · Sites in Egypt
Ages 10–18 · Women only
A study can be open while its sites in Egypt have not opened yet or have stopped. Only those recruiting at a site in Egypt →
Of the 14 Nocturnal Enuresis studies recruiting now, 5 (36%) set no upper age limit and 9 (64%) stop at 75 or younger; 8 take children under 18; 2 take healthy volunteers.
This study: 5 Years to 30 Years · all sexes · no healthy volunteers.
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22 studies; the count open now beside each. This study's row is marked.
First in 2017; this study’s year is marked. 3 started in 2023.
By drug class, each counting the studies that test any of its medicines:
This study's planned enrollment of 40 is below the median of 66 across 77 interventional studies indexed under Nocturnal Enuresis.
Median enrollment 95 across the 18 interventional studies, 190 across the 4 observational. Of the 10 that completed or were terminated, 0 (0%) have results posted.
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None of the 22 has an industry lead sponsor. The 10 most frequent:
University of Alexandria is the lead sponsor of 59 studies on the registry; 5 are open to participants now.
University of Alexandria has 1 study filed under Nocturnal Enuresis — fewer than ten, so there is no comparison to draw.
2 of the studies in Nocturnal Enuresis with a site in Egypt that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07930351Hungarian University of Sports ScienceAerobic Exercise Added to Diaphragmatic Breathing for Nocturnal Enuresis in Overweight and Obese Children | 2027-01-25 |
| NCT07776977Al-Azhar UniversityBedtime Device Restriction and Desmopressin in PMNE. | 2027-05 |
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Among the 22 studies in Nocturnal Enuresis with a site in Egypt, from their registry updates:
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A prospective randomized trial to study the effect of spinal magnetic stimulation versus posterior tibial neuromodulation in the treatment of monosymptomatic nocturnal enuresis.
Nocturnal enuresis is defined as "nighttime bedwetting in children aged five years or older.Currently available treatment options for nocturnal enuresis include medication, wetting alarms, lifestyle changes, sacral magnetic stimulation, and posterior tibial neurmodulation.
Magnetic stimulation is a valid method for stimulation of sacral as functional electrical stimulation. It generates a more powerful and deeper electrical field than that produced by conventional electrical stimulators. So, magnetic stimulation could be considered an attractive form of electrical therapy, being relatively painless, non-invasive and free from side effects.Peripheral neuromodulation is the modulation of the physiologic behavior of the nerve by electrical stimulation. Posterior tibial neuromodulation is an effective method in treatment of urinary incontinence
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The American Psychiatric Association’s manual of mental health diagnoses. DSM-5 (2013, revised as DSM-5-TR in 2022) replaced DSM-IV, and some studies still name the older edition. “Meets DSM criteria for …” means diagnosed by that edition’s diagnostic criteria, usually by a clinician in an interview.
DSM diagnostic criteria
The American Psychiatric Association’s manual of mental health diagnoses. DSM-5 (2013, revised as DSM-5-TR in 2022) replaced DSM-IV, and some studies still name the older edition. “Meets DSM criteria for …” means diagnosed by that edition’s diagnostic criteria, usually by a clinician in an interview.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Spinal magnetic stimulation group will receive repetitive spinal magnetic stimulation sessions for a total of 12 sessions. Using the Neuro-MS/D machine, circular coil will be used to stimulate S2,3 and 4 sacral roots. The outer rim of the coil will be positioned in the midline over the sacral vertebrae (approximately 5 cm above the natal cleft, which approximates to the level of S2) Intensities will be adjusted to 50-70 % of maximal output (2.2 Tesla), stimulation frequency will be fixed at 15 Hz, burst length = 10 seconds, inter-burst interval = 30 seconds with a total of 1500 pulses
Other: Rehabilitation
Neuromodulation group will receive 12 sessions of bilateral transcutaneous posterior tibial neuromodulation using (Myomed 632®, Enraf Nonius, Delft, Netherlands) machine, the active rubber surface was placed behind the medial malleolus and the reference electrode was placed 10 cm proximal. Adjustment of the electric current was as follows: continuous current, pulse duration 200 ms, frequency 20 Hz; each session lasts for 30 min. The current intensity was adjusted according to the tolerance of the patient or until the big toe curls into plantar flexion
Other: Rehabilitation
rehabilitation sessions using spinal magnetic stimulation or neuromodulation
Frequency of bed wetting
Number of bed wettings/ week
Time frame: one month
Visual analogue scale to determine how much the enuresis affected his/her life.
Visual analogue scale from zero to ten (zero indicates no effect, 10 indicates severe bothersome
Time frame: three months
Plan to share: Yes — All data will be available with the corresponding author to be shared with other researchers for three years after publishing the study
Supporting information: Study protocol, Statistical analysis plan, Informed consent form, Clinical study report
Time frame: three years after publication
Access criteria: Researchers can contact the corresponding author directly through e-mail
No publications or documents are linked to this record.
Start is estimated for Feb 2023; primary completion for Jun 2023, 4 months later.
Of 41 interventional studies with no phase under Nocturnal Enuresis, half reached primary completion within 27 months of starting (the median), counting those still running; a quarter within 9 and three quarters within 49. This study's planned 4 months is below that.
How these figures are worked out, and which studies are left out of them.
This study is status unknown, as verified in Jan 2023. You cannot join it, but the record below documents what was studied.
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University of Alexandria