ClinicalTrials.gg
CompletedNCT05206253Updated May 29, 2024

Effectiveness of Egg Versus Whey Protein Powder During Resistance Training

An interventional study of Whole egg powder and Whey protein powder in Muscle Atrophy, sponsored by University of Saskatchewan. Completed at 2 sites in Canada. Open to participants aged 18 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-05-29.

Sponsored by University of Saskatchewan · Not applicable, Interventional, and Other

Phase
Not applicable
Study type
Interventional
Enrollment
115
Allocation
Randomized
Ages
18 Years to 35 Years
Sex
All
01

Study summary

Consumption of whole eggs has recently been shown to stimulate muscle protein synthesis to a greater degree than consumption of egg whites after a resistance training session. It is theorized that the egg yoke contains bio-active nutrients that enhance the protein provided by egg whites. The study will evaluate the effect of whole egg powder compared to whey protein powder and placebo over 12 weeks of resistance training in men and women who are participating in resistance training programs.

Read the detailed description

Consuming whole eggs after resistance training sessions appears to be more effective for simulating muscle protein synthesis that simply consuming egg whites. The egg yolks might enhance the effect of protein derived from egg whites. The study will compare post-exercise supplementation with about 30 grams of protein derived from whole egg powder versus whey protein powder and placebo (maltodextrin) over a 12-week resistance training program. Resistance-trained men and women (n=120) will be randomized to consume either the whole-egg powder, whey protein powder or maltodextrin after resistance training 6 times per week for 12 weeks. The primary outcome measure is change in lean tissue mass. Secondary measures include change in fat mass, change in arm and leg muscle thickness, change in bench press, squat, and knee extension strength, and change in fasting blood glucose.

02

Conditions studied

  • Muscle Atrophy

Browse trials for

03

In context

Muscular Atrophy

503 studies on the registry are indexed under Muscular Atrophy; 94 are open to participants now.

This study's enrollment of 115 is above the median of 34 across 342 interventional studies indexed under Muscular Atrophy.

Browse Muscular Atrophy studies →

Lead sponsor

University of Saskatchewan is the lead sponsor of 243 studies on the registry; 34 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 35 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Resistance training experience for at least one year

Exclusion criteria

Exclusion Criteria:

  • Having taken any nutritional supplements the past 30 days
  • Currently using anabolic steroids
  • Currently taking corticosteroids
  • Allergies to dairy or egg products
  • Identifying any medical conditions as determined by the "Get Active Questionnaire"
05

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Quadruple (Participant, Care provider, Investigator, Outcomes assessor)
Enrollment
115 participants (actual)

Study arms

  • Experimental
    Whole egg powder

    Dietary supplementation with whole egg powder after resistance training sessions

    Dietary Supplement: Whole egg powder

  • Active comparator
    Whey protein powder

    Dietary supplementation with whey protein powder after resistance training sessions

    Dietary Supplement: Whey protein powder

  • Placebo comparator
    Maltodextrin placebo

    Dietary supplementation with maltodextrin placebo after resistance training sessions

    Dietary Supplement: Maltodextrin placebo

Interventions

  • Dietary supplementWhole egg powder

    Nutritional supplementation during a 12 week resistance training program

  • Dietary supplementWhey protein powder

    Nutritional supplementation during a 12 week resistance training program

  • Dietary supplementMaltodextrin placebo

    Nutritional supplementation during a 12 week resistance training program

06

What researchers measure

Primary outcomes

  1. Change in lean tissue mass

    Lean tissue mass measured by DXA

    Time frame: 12 weeks

Secondary outcomes

  1. Change in fat mass

    Fat mass measured by DXA

    Time frame: 12 weeks

  2. Change in biceps muscle thickness

    biceps muscle thickness measured by ultrasound

    Time frame: 12 weeks

  3. Change in triceps muscle thickness

    triceps muscle thickness measured by ultrasound

    Time frame: 12 weeks

  4. Change in quadriceps muscle thickness

    quadriceps muscle thickness measured by ultrasound

    Time frame: 12 weeks

  5. Change in hamstrings muscle thickness

    hamstrings muscle thickness measured by ultrasound

    Time frame: 12 weeks

  6. Change in bench press strength

    Bench press strength (kg)

    Time frame: 12 weeks

  7. Change in leg squat strength

    Leg squat strength (kg)

    Time frame: 12 weeks

  8. Change in knee extension strength

    Isokinetic knee extension torque

    Time frame: 12 weeks

  9. Change in fasting glucose

    Fasting glucose

    Time frame: 12 weeks

07

Study locations

2 sites
  • University of Regina
    Regina, Saskatchewan S4S 0A2, Canada
  • University of Saskatchewan
    Saskatoon, Saskatchewan S7N5B2, Canada
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 29, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05206253
Collaborators
Egg Farmers of Canada
Responsible party
Phil Chilibeck (Professor, University of Saskatchewan) — Principal investigator
First posted
Jan 25, 2022
Start date
May 30, 2022
Primary completion
Aug 31, 2023
Completion
Aug 31, 2023
Last update
May 29, 2024

Study contacts

Philip Chilibeck, Ph.D.
principal investigator · University of Saskatchewan
Darren Candow, Ph.D.
principal investigator · University of Regina

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2024. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion