An observational study in Acute Coronary Syndrome, Atrial Fibrillation and Kidney Diseases, sponsored by Medical University of Bialystok. Active, not recruiting at 1 site in Poland. Per ClinicalTrials.gov, last updated 2024-06-21.
Sponsored by Medical University of Bialystok · Observational
The effects of air pollution on the frequency of hospital admissions and mortality due to acute coronary syndromes, atrial fibrillation, and renal disfunction are noted also in areas perceived as pollution-free (due to the lack of large industry). The aim of the project is to assess the impact of air pollution in Eastern Poland on regional public health.
The project will be conducted in Eastern Poland - the area characterized by unique natural features, large areas covered by forests, lack of factories, and relatively low industrialization. On the other hand, the region is also characterized by low socioeconomic status, in the cold season the residents' suboptimal heating choices are in result posing a major anthropogenic threat to air quality in the form of low emissions. The vast majority of studies on air pollution were conducted in highly polluted areas, in which patients are exposed to moderate and extreme concentrations of pollutants. Taking into consideration the scarce number of surveys from areas with a low level of pollution the investigators intend to analyze the relationship between air pollution and cardiovascular and renal outcomes in Eastern Poland. The examination of the impact of so-called "Polish smog" on mortality and morbidity in the study area is not without significance. It would be the first major study of the impact of this type of pollution on human health.
In the subsequent part of the study, we will evaluate the effects of Polish smog in the entire country.
In light of extant body of literature, the following will be considered as the public health indicators: acute coronary syndromes, episodes of atrial fibrillation, ischemic strokes, kidney disease hospitalizations or emergency room visits, cardiovascular and renal mortality.
2,593 studies on the registry are indexed under Ischemic Stroke; 930 are open to participants now.
This study's planned enrollment of 8,300,000 is above the median of 300 across 777 observational studies indexed under Ischemic Stroke.
Browse Ischemic Stroke studies →Medical University of Bialystok is the lead sponsor of 68 studies on the registry; 17 are open to participants now.
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The study population will be based on residents of Eastern Poland. This term covers 5 voivodships - Warmińsko-Mazurskie, Podlaskie, Lubelskie, Świętokrzyskie, Podkarpackie - with total area of 99,004 km2. The inhabitants of this region constitute 21.3% of the population of Poland and 1.6% of the population of the European Union. The area characterized by unique natural features, large areas covered by forests, lack of factories, and relatively low industrialization is not free of air pollution. As the region is also characterized by low socioeconomic status, in the cold season the residents' suboptimal heating choices are in result posing a major anthropogenic threat to air quality in the form of low emissions.
Exclusion Criteria:
Data on hospitalization for acute coronary syndromes were obtained and extracted from the National Health Fund reports. In the present analysis, we used data from patients registered as residents in the Podlaskie, Lubelskie, Podkarpackie, Świetokrzyskie, and Warminsko-Mazurskie voivodeships from January 1, 2011 to December 31, 2020. The set of variables that were subjected to the analysis included demographic features and ICD-10 codes. The diagnosis was based on reports obtained from to the National Health Fund, and these reports have not been reviewed with patient hospital documentation.
Other: Impact of air pollution
Data on hospitalization for atrial fibrillation were obtained and extracted from the National Health Fund reports. In the present analysis, we used data from patients registered as residents in the Podlaskie, Lubelskie, Podkarpackie, Świetokrzyskie, and Warminsko-Mazurskie voivodeships from January 1, 2011 to December 31, 2020. The set of variables that were subjected to the analysis included demographic features and ICD-10 codes. The diagnosis was based on reports obtained from to the National Health Fund, and these reports have not been reviewed with patient hospital documentation.
Other: Impact of air pollution
Data on hospitalization for kidney diseases were obtained and extracted from the National Health Fund reports. In the present analysis, we used data from patients registered as residents in the Podlaskie, Lubelskie, Podkarpackie, Świetokrzyskie, and Warminsko-Mazurskie voivodeships from January 1, 2011 to December 31, 2020. The set of variables that were subjected to the analysis included demographic features and ICD-10 codes. The diagnosis was based on reports obtained from to the National Health Fund, and these reports have not been reviewed with patient hospital documentation.
Other: Impact of air pollution
Data on mortality were collected from the National Statistical Office in Poland. These include information on all the deaths recorded in the Podlaskie, Lubelskie, Podkarpackie, Świetokrzyskie, and Warminsko-Mazurskie voivodeships from January 1, 2011 to December 31, 2020 The records included sex and age of people who had died, and the causes of deaths were classified according to codes in the International Classification of Diseases-10th Revision (ICD-10).
Other: Impact of air pollution
Data on mortality were collected from the National Statistical Office in Poland. These include information on all the deaths recorded in the Podlaskie, Lubelskie, Podkarpackie, Świetokrzyskie, and Warminsko-Mazurskie voivodeships from January 1, 2011 to December 31, 2020 The records included sex and age of people who had died, and the causes of deaths were classified according to codes in the International Classification of Diseases-10th Revision (ICD-10).
Other: Impact of air pollution
Data on mortality were collected from the National Statistical Office in Poland. These include information on all the deaths recorded in the Podlaskie, Lubelskie, Podkarpackie, Świetokrzyskie, and Warminsko-Mazurskie voivodeships from January 1, 2011 to December 31, 2020 The records included sex and age of people who had died, and the causes of deaths were classified according to codes in the International Classification of Diseases-10th Revision (ICD-10).
Other: Impact of air pollution
Data on hospitalization for ischemic strokes were obtained and extracted from the National Health Fund reports. In the present analysis, we used data from patients registered as residents in the Podlaskie, Lubelskie, Podkarpackie, Świetokrzyskie, and Warminsko-Mazurskie voivodeships from January 1, 2011 to December 31, 2020. The set of variables that were subjected to the analysis included demographic features and ICD-10 codes. The diagnosis was based on reports obtained from to the National Health Fund, and these reports have not been reviewed with patient hospital documentation.
Other: Impact of air pollution
To assess the short- and long- term impact of air pollution
Number of acute coronary syndromes related to the impact of air pollution.
Short- and long- term influence of air pollution on the number of hospital admissions for acute coronary syndromes.
Time frame: Through study completion, an average of 1 year
Number of atrial fibrillation episodes related to the impact of air pollution.
Short- and long- term influence of air pollution on the number of hospital admissions for atrial fibrillation.
Time frame: Through study completion, an average of 1 year
Number of hospitalizations due to kidney diseases related to the impact of air pollution.
Long- term influence of air pollution on the number of hospital admissions for kidney disease.
Time frame: Through study completion, an average of 1 year
Number of hospitalizations due to acute kidney diseases related to the impact of air pollution.
Long- term influence of air pollution on the number of hospital admissions for kidney disease.
Time frame: Through study completion, an average of 1 year
Number of patients under hemodialysis related to the impact of air pollution.
Long- term influence of air pollution on the number of hospital admissions for kidney disease.
Time frame: Through study completion, an average of 1 year
Number of ischemic strokes related to the impact of air pollution.
Short- and long- term influence of air pollution on the number of hospital admissions for ischemic strokes.
Time frame: Through study completion, an average of 1 year
Cardiovascular mortality
Short- and long- term influence of air pollution on the number of cardiovascular mortality.
Time frame: Through study completion, an average of 1 year
Neoplasm mortality
Short- and long- term influence of air pollution on neoplasm mortality.
Time frame: Through study completion, an average of 1 year
Kidney disease mortality
Short- and long- term influence of air pollution on mortality related to renal function.
Time frame: Through study completion, an average of 1 year
This study is active, not recruiting, as verified in Jun 2024. You cannot join it, but the record below documents what was studied.
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Medical University of Bialystok