An interventional study of Pulsed Ultrasound and Pulsed Electromagnetic field in Osteo Arthritis Knee and Ultrasound Therapy; Complications, sponsored by Horus University. Completed at 1 site in Egypt. Open to participants aged 40 Years to 55 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-09-25.
Sponsored by Horus University · Not applicable, Interventional, and Treatment
This study will be carried out to combine the effect of PEMF and PUT on pain, function, and ROM in patients with knee OA.
Osteoarthritis (OA) is one of the most frequent illnesses in the world, affecting the knee joint in particular. Osteoarthritis of the knee is the most common cause of physical limitations and a decline in quality of life. OA of the knee affects 250 million individuals worldwide (3.6 percent of the population). According to the World Health Organization's study on the global burden of illness, knee OA is expected to become the eighth-most
Ultrasound is one of the most often utilized and misunderstood treatment techniques. Ultrasound can help in the treatment or rehabilitation of musculoskeletal problems when utilized appropriately. When it is administered wrongly, however, the therapy provides little benefit at best, and at worst, the desired physiological effects are restricted or hindered.
Electrotherapy is frequently used for the treatment of different musculoskeletal disorders, The most common types of electrotherapy are ultrasound (US), iontophoresis, laser therapy, electromagnetic therapy, and transcutaneous electrical nerve stimulation (TENS). To our knowledge, no previous clinical trials have combined the effectiveness of PEMF and PUST in the treatment of knee OA. Therefore, this study will be conducted to combine the efficacy of PEMF and PUST in the treatment of knee osteoarthritis.
4,398 studies on the registry are indexed under Osteoarthritis; 582 are open to participants now.
This study's enrollment of 80 is above the median of 70 across 3,440 interventional studies indexed under Osteoarthritis.
Browse Osteoarthritis studies →Horus University is the lead sponsor of 31 studies on the registry; 9 are open to participants now.
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Subjects diagnosed with moderate unilateral knee OA according to the American College of Rheumatology criteria
Exclusion Criteria:
Patients with the following criteria will be excluded from participating in this study:
Twenty subjects will receive PUT, plus an exercise program.
Device: Pulsed Ultrasound · Other: Traditional exercise program
Twenty subjects will receive PEMF, plus an exercise program.
Device: Pulsed Electromagnetic field · Other: Traditional exercise program
Twenty subjects will receive PUT, PEMF, plus an exercise program.
Device: Pulsed Ultrasound · Device: Pulsed Electromagnetic field · Other: Traditional exercise program
Twenty subjects will receive sham PEMF and sham PUT plus exercises program.
Other: Traditional exercise program · Device: Sham Pulsed US & Electromagnetic field
Active US therapy will be administered using a device 4cm², 1- MHz US with a sound-head area of effective 4cm, radiating area of 3.5 to a beam non-uniformity ratio of cm². 5:1, and a therapeutic dose of approximately 112.5J/ That is, the pulsed US will be delivered for 9.5 minutes with a peak intensity of 1W/cm² at a 20% duty cycle, to achieve a spatial-temporal average intensity of 0.2W
The patient's knee will be placed between 2 plates coil applicator generating a magnetic field intensity of 1.5 mT and a frequency of 75Hz.
Stretching exercises, Isometric quadriceps exercise, Straight leg raising (SLR) exercise, Isometric hip adduction exercise, Hip abductor strengthening, Hip extensor strengthening, Hip external rotator strengthening
The patients will receive Sham Pulsed US \& Electromagnetic field.
Pain intensity
Assessing the change in pain intensity using visual analogue scale which consists of a 10-cm line anchored at each end. Score of 10 means (Worest possible pain) while score of 0 means (No pain).
Time frame: at baseline and after 4 weeks of intervention
Dynamic balance
Assessing the change in Dynamic balance using timed up and go test. It will be used to asses patients functional mobility. The patient will be asked to rise from a standard armchair, walk at a safe and comfortable pace to a mark 3 m away, then return to a sitting position in the chair, using gait aids and chair armrests to assist with sit to stand as needed.
Time frame: at baseline and after 4 weeks of intervention
Range of motion of knee
Assessing the change in knee rane of motion using electrogoniometer.
Time frame: at baseline and after 4 weeks of intervention
Pain, Stiffness and function
Assessing the change in Pain, Stiffness and function using Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). It consists of three subscales regarding pain, stiffness, and physical function with five, two, and 17 questions, respectively. Answers for these 24 questions are scored on five-point Likert scales (none = 0, slight = 1, moderate = 2, severe = 3, extreme = 4) with total scores ranging from 0 to 96. Higher scores indicate greater disease severity.
Time frame: at baseline and after 4 weeks of intervention
Walking ability
Assessing the change in Walking ability using the 10-meter walk test.which is reliable and valid test in patients with OA , measuring the required time for walking on a standard flat surface of 10 m.
Time frame: at baseline and after 4 weeks of intervention
Plan to share: Undecided
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This study is completed, as verified in Sep 2023. You cannot join it, but the record below documents what was studied.
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