An observational study in Appendicitis Acute, sponsored by KBC Split. Status unknown at 1 site in Croatia. Open to participants aged 5 Years to 17 Years. Per ClinicalTrials.gov, last updated 2022-04-07.
Sponsored by KBC Split · Observational
Acute appendicitis is a common and potentially serious medical condition which can be difficult to diagnose, especially in pediatric patients. To help recognize patients with acute appendicitis, number of laboratory and radiological test are used. Previous research has shown that Circulating Human Leucine-rich α-2-glycoprotein (LGR1) in the blood can be elevated in pediatric patients with acute appendicitis. The aim of this research is to analyse whether LGR1 levels in saliva can be used as a less invasive diagnostic method in pediatric patients with suspected acute appendicitis.
419 studies on the registry are indexed under Appendicitis; 67 are open to participants now.
This study's planned enrollment of 90 is below the median of 200 across 151 observational studies indexed under Appendicitis.
Browse Appendicitis studies →KBC Split is the lead sponsor of 4 studies on the registry; 1 is open to participants now.
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Patients from 5 to 17 years of age, presenting with acute abdominal pain consistent with diagnosis of acute appendicitis, to Emergency Surgery Department at the University Hospital Split.
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Exclusion Criteria:
Patients with acute appendicitis, after surgery and with pathohistological specimen confirmation.
Diagnostic Test: Blood specimen collection · Diagnostic Test: Saliva specimen collection
Patients without acute appendicitis, after laboratory, clinical and/or radiological exclusion of acute admittance.
Diagnostic Test: Blood specimen collection · Diagnostic Test: Saliva specimen collection
Blood specimen collection for analysis of CRP (C-reactive protein), WBC (White blood cells) and LRG1 (Circulating Human Leucine-rich α-2-glycoprotein) levels
Saliva specimen collection for analysis of LRG1 (Circulating Human Leucine-rich α-2-glycoprotein) levels
Level of LGR1 protein in blood
Levels of LGR1 protein in blood and saliva as measured by ELISA test
Time frame: 72 hours
Level of LGR1 protein saliva
Levels of LGR1 protein in saliva as measured by ELISA test
Time frame: 72 hours
Plan to share: No
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This study is status unknown, as verified in Mar 2022. You cannot join it, but the record below documents what was studied.
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