An interventional study of Oesophageal pacing after left atrial posterior wall isolation in Persistent Atrial Fibrillation and Atrial Fibrillation Ablation, sponsored by University Hospital Plymouth NHS Trust. Completed at 1 site in United Kingdom. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2021-10-21.
Sponsored by University Hospital Plymouth NHS Trust · Not applicable, Interventional, and Diagnostic
Patients undergoing hybrid AF ablation second stage catheter ablation have the posterior left atrium mapped to see it if is electrically isolated. This is done via a standard electrophysiogical study in accordance with routine clinical practice.
Investigators propose to check left atrium posterior wall isolation via oesophageal pacing and compare this to findings from invasive study
Oesophageal temporary pacing of the heart is an established treatment in heart block and several catheters are licenced for this purpose with minimal procedural risks. Due to the position of the oesophagus, pacing from the oesophagus could sense and pace the posterior left atrium. If the posterior wall could be demonstrated to be electrically isolated with oesophageal pacing then invasive electrophysiological study such as the second stage of a hybrid AF ablation would be unnecessary.
This would save patients from undergoing invasive left atrial mapping and exposure to the consequent risks of the procedure.
3,872 studies on the registry are indexed under Atrial Fibrillation; 926 are open to participants now.
This study's enrollment of 52 is below the median of 144 across 2,381 interventional studies indexed under Atrial Fibrillation.
Browse Atrial Fibrillation studies →University Hospital Plymouth NHS Trust is the lead sponsor of 53 studies on the registry; 7 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Inclusion Criteria: • subjects capable of giving informed consent,
Exclusion Criteria:
Patients undergoing atrial fibrillation ablation to isolate the left atrial posterior wall via catheter or staged hybrid ablation.
Device: Oesophageal pacing after left atrial posterior wall isolation
Following AF ablation with the aim of isolating the left atrial posterior wall oesophageal pacing and sensing is performed to check for left atrial posterior wall. entrance and exit block.
Left atrial posterior wall isolation
Measured via invasive left atrial mapping
Time frame: Through study completion, an average of 4 years
Complication rate
Documentation of the number of complications caused by the oesophageal pacing procedure
Time frame: Through study completion, an average of 4 years
Feasibility of using device
The success rate of left atrial posterior wall isolation.
Time frame: Through study completion, an average of 4 years
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Dec 2020. You cannot join it, but the record below documents what was studied.
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University Hospital Plymouth NHS Trust