An observational study in Hypertension, Gut Microbiota and Diet, sponsored by Taipei Medical University. Status unknown at 1 site in Taiwan. Open to participants aged 65 Years to 80 Years. Per ClinicalTrials.gov, last updated 2023-04-18.
Sponsored by Taipei Medical University · Observational
Recent animal and human studies have found the relationship between the composition of the gut microbiota and hypertension, but some studies did not have a detailed evaluation of the diet content, which could be an important effect on gut microbiota. Moreover, most of these studies were finished in Western countries, in which the dietary patterns were significantly different from those in Chinese regions. This study intends to establish Taiwanese local data to explore the differences in the composition of gut microbiota among hypertensive patients and normotensive subjects.
The investigators plan to enroll total 70 hypertensive and normotensive cases from the elderly health examination in Cathay General Hospital, who are aged from 65 to 80 years. Body mass index and blood samples for biochemical analysis such as blood sugar and cholesterol levels are taken, and fecal samples are collected for analysis of gut microbiota, which is characterized by 16S ribosomal RNA gene sequencing. Besides, the diet and nutrients intake are recorded and calculated by licensed dietitian. Through the exploration of gut microbiota in hypertensive patients, the results can be the reference for clinical treatment.
6,689 studies on the registry are indexed under Hypertension; 965 are open to participants now.
This study's planned enrollment of 70 is below the median of 210 across 1,359 observational studies indexed under Hypertension.
Browse Hypertension studies →Taipei Medical University is the lead sponsor of 245 studies on the registry; 56 are open to participants now.
Counted across the registry records on this site, refreshed daily.
People who join the Elderly Health Examination Program in Cathay General Hospital in 2021
Exclusion Criteria:
SBP \>=140mmHg, DBP \>=90mmHg, or use of antihypertensive drug
SBP \<=140mmHg and DBP \<=90mmHg without use of antihypertensive drug
The difference of gut microbiota composition between the two groups
The differential OTUs (operational taxonomic units) between the two groups
Time frame: immediately after the enrollment completes
This study is status unknown, as verified in Jan 2023. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Taipei Medical University