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Status unknownNCT05044247Updated Sep 28, 2021

The Effect of Both Ultrasound and Fluoroscopy Guide Erector Spinae Plane Blocks

An interventional study of ESP blocks in Pain, Chronic and Pain, Postoperative, sponsored by National Taiwan University Hospital. Status unknown at 1 site in Taiwan. Open to participants aged 20 Years and older. Per ClinicalTrials.gov, last updated 2021-09-28.

Sponsored by National Taiwan University Hospital · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Sep 2020), so the status shown — last known as Recruiting — may be out of date.

From the registry’s dates

  • Registered 4 months after the study started (first participant enrolled Apr 2021, registered Sep 2021).
Phase
Not applicable
Study type
Interventional
Enrollment
70
Allocation
Not applicable
Ages
20 Years and older
Sex
All
01

Study summary

Since the original publication on the erector spinae plane (ESP) block in 2016, the technique of the ESP block has evolved significantly in the last few years. Current reports suggest that the ESP block provides adequate analgesia in thoracic and abdominal sites in a post-surgical and chronic pain patient. However, there were still inconsistencies and unclear spread of local anesthetics in ultrasound guide ESP block.

This study focusing on the spread of local anesthetic in ESP block under ultrasound and fluoroscopy and possible mechanisms of action.

Read the detailed description

The erector spinae plane (ESP) block was first described by Forero et al. Considering the spread of local anesthetic in the ESP block, it can block more extensive spinal nerves. Therefore, since the first publication, the ESP block has been reported as an effective analgesic for several types of pain and has been used mainly in thoracic surgery. It also used in abdominal surgery, nephrectomy, hernia surgery, and hip surgery, among others. Additionally, the ESP block used not only acute pain management but also chronic pain management.

The spread of local anesthetic in the ESP block investigated in several ways, such as computed tomography (CT) imaging of cadavers, fluoroscopy, chest radiography, and patients' CT imaging. These investigations show that local anesthetics in the ESP block spread to the upper and lower sides of the interfascial plane between the erector spine muscle and the underlying transverse process. Additionally, the local anesthetic spreads beyond the transverse process to reach the costotransverse junctions, after which it permeates the paravertebral space.

Despite the many publications on ESP blocks, there are still inconsistencies and unclear aspects of the technique, such as the spread of local anesthetic and action mechanisms This study focuses on the spread of local anesthetic in ESP block under ultrasound and fluoroscopy and possible mechanisms of action.

02

Conditions studied

  • Pain, Chronic
  • Pain, Postoperative
03

In context

Pain, Postoperative

5,093 studies on the registry are indexed under Pain, Postoperative; 1,140 are open to participants now.

This study's planned enrollment of 70 is close to the median of 75 across 4,344 interventional studies indexed under Pain, Postoperative.

Browse Pain, Postoperative studies →

Lead sponsor

National Taiwan University Hospital is the lead sponsor of 2,563 studies on the registry; 569 are open to participants now.

Of its 11 completed or terminated interventional studies of FDA-regulated products, 2 (18%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  1. Thirty-five patients in each group of breast tumor surgery and pain intervention procedure patients.
  2. Age > 20

Exclusion criteria

Exclusion Criteria:

  1. Unable to complete questionnaires.
  2. With coagulopathy
  3. History of thoracic spine trauma or surgery.
  4. Allergy to contrast local anesthetics and medium (Iohexol)
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
70 participants (estimated)

Study arms

  • Experimental
    ESP block

    ESP block under mixed local anesthetics, betamethasone agent

    Procedure: ESP blocks

Interventions

  • ProcedureESP blocks

    ultrasound and fluoroscopy to identify the spread of drug

06

What researchers measure

Primary outcomes

  1. Pain scale

    reduction of Visual Analogue Scale

    Time frame: 12 months

07

Study locations

1 of 1 sites recruiting
  • National Taiwan University Cancer Center
    Taipei county, Taiwan
    • Wen-Ying Lin · Contact
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 28, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT05044247
Lead sponsor
National Taiwan University Hospital
Responsible party
Sponsor
First posted
Sep 14, 2021
Start date
Apr 20, 2021
Primary completion
Sep 2021 (estimated)
Completion
Sep 2021 (estimated)
Last update
Sep 28, 2021

Study contacts

Wen-Ying Lin
Contact
ying434@gmail.com
0223220322 ext. 38133

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Sep 2020. You cannot join it, but the record below documents what was studied.

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