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Status unknownNCT04981990Updated Aug 25, 2021

Single Lung Ventilation Versus Two Lung Ventilation

An interventional study of Single lung ventilation by double lumen endotracheal tube and Two lung ventilation by conventional single lumen endotracheal tube in Hypoxemia and Single Lung Ventilation, sponsored by Ain Shams University. Status unknown at 1 site in Egypt. Open to participants aged 21 Years and older. Per ClinicalTrials.gov, last updated 2021-08-25.

Sponsored by Ain Shams University · Not applicable, Interventional, and Other

The sponsor has not verified this record recently (last verified Aug 2021), so the status shown — last known as Recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
60
Allocation
Randomized
Ages
21 Years and older
Sex
All
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Study summary

Hypoxia in single lung ventilation versus two lung ventilation in video assisted lung surgeries

Read the detailed description

Incidence of hypoxia in single lung ventilation by double lumen endotracheal tube "of choice in lung surgeries" versus incidence of hypoxia in two lung ventilation by conventional single lumen endotracheal tube "intermittent two lung ventilation"

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Conditions studied

  • Hypoxemia
  • Single Lung Ventilation

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In context

Hypoxia

1,231 studies on the registry are indexed under Hypoxia; 241 are open to participants now.

This study's planned enrollment of 60 is above the median of 45 across 853 interventional studies indexed under Hypoxia.

Browse Hypoxia studies →

Lead sponsor

Ain Shams University is the lead sponsor of 1,876 studies on the registry; 423 are open to participants now.

Of its 32 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
21 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Age group: Adult patients from age of 21 years to 60 years
  • Sex: Both sexes
  • ASA Classification: patients with ASA classification II, III.
  • Elective lung surgeries using video assisted thoracoscopic surgeries.

Exclusion criteria

Exclusion Criteria:

  • Patients refuse to give informed consent.
  • ASA Classification: ASA IV.
  • Failure of thoracoscopic surgeries and continue as open thoracotomy
  • Patients with ischemic heart diseases, where hypoxemia might be preexisting, or patient be more vulnerable to hypoxemia whatever the technique or time of hypoxia.
  • Emergency lung surgeries.
  • Patients underwent previous lung surgeries of any cause.
  • Patients with pathology to the non-operated side.
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Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
60 participants (estimated)

Study arms

  • Active comparator
    Single lung ventilation

    Using double lumen endotracheal tube and lung isolation

    Procedure: Single lung ventilation by double lumen endotracheal tube

  • Active comparator
    Two lung ventilation

    Using conventional single lumen endotracheal tube and intermittent two lung ventilation

    Procedure: Two lung ventilation by conventional single lumen endotracheal tube

Interventions

  • ProcedureSingle lung ventilation by double lumen endotracheal tube

    Single lung ventilation using double lumen endotracheal tube and isolation of the operated lung during surgery to create ideal surgical field

  • ProcedureTwo lung ventilation by conventional single lumen endotracheal tube

    Intermittent two lung ventilation so that no significant hypoxia occurs with creating optimum surgical field

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What researchers measure

Primary outcomes

  1. Incidence of hypoxemia

    Hypoxemia in single and two lung ventilation by serial arterial blood gases

    Time frame: Intraoperative to first 24 hours post operative

Secondary outcomes

  1. Incidence of failure to correct Hypoxemia in single lung ventilation

    Stop lung isolation and procedure using two lung ventilation to correct hypoxia

    Time frame: Intraoperative

  2. Incidence of failure of two lung ventilation to create optimum surgical field

    Frequent stopping of ventilation and the surgent can't access the surgical field easily

    Time frame: Intraoperative

  3. Incidence of post operative complications

    Any associated complications

    Time frame: First 24 hours post operative

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Study locations

1 of 1 sites recruiting
  • Aun Shams University Hospitals
    Cairo, Egypt
    Recruiting
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References and documents

Study documents

  • Protocol and statistical analysis plan · Jan 1, 2021
  • Informed consent form · Jan 1, 2021

Documents are hosted by the registry — open the source record to download them.

Individual participant data

Plan to share: Yes — All study data will be open to other researchers

Supporting information: Study protocol, Sap, Csr

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 25, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04981990
Lead sponsor
Ain Shams University
Responsible party
Esraa Abdellatif (Anesthesia resident, principal investigator, Ain Shams University) — Principal investigator
First posted
Jul 29, 2021
Start date
Mar 1, 2021
Primary completion
Aug 25, 2021
Completion
Aug 25, 2021 (estimated)
Last update
Aug 25, 2021

Study contacts

Esraa Abdellatif
Contact
esraa301993@gmail.com
01119895491
Esraa Abdellatif, M.B., B.Ch.
principal investigator · Anesthesiology department
Omar El safty, MD
study chair · Anesthesiology department
Salwa Omar, MD
study director · Anesthesiology department
Mohamed Taeimah, MD
study director · Anesthesiology department

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Aug 2021. You cannot join it, but the record below documents what was studied.

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