An observational study in BPD - Bronchopulmonary Dysplasia, sponsored by Pediatrix. Completed at 1 site in United States. Per ClinicalTrials.gov, last updated 2024-11-19.
Sponsored by Pediatrix · Observational
Assess the impact of steroid, diuretic, and fluid practices on BPD outcomes in extreme premature infants in the Banner - University Medical Center Phoenix (BUMCP) neonatal intensive care unit (NICU).
The investigators propose performing a retrospective analysis of the current respiratory management methods to potentially find a correlation between the number of steroid doses administered, the timing of initiation of steroid therapy and the effect on premature infants at risk for developing BPD. The investigators are also going to explore the number and timing of diuretic medications and average fluid intake.
362 studies on the registry are indexed under Bronchopulmonary Dysplasia; 85 are open to participants now.
This study's enrollment of 175 is above the median of 150 across 99 observational studies indexed under Bronchopulmonary Dysplasia.
Browse Bronchopulmonary Dysplasia studies →Pediatrix is the lead sponsor of 34 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Infants admitted to the BUMCP NICU at \<30 weeks and/or \<1500 grams (g)
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Infants born at \<30 weeks and/or \<1500g that were admitted to BUMCP between January 1, 2019 and December 31, 2020
Other: No interventions or procedures
This is a retrospective observational study and data will be collected from the subject's existing medical record. No interventions or procedures will be required for this study.
To assess the impact of steroid practices on BPD outcomes in these infants
- The incidence of BPD stratified into three stages based on the type of support required at 36 weeks CGA
Time frame: 30 days
To assess the impact of steroid practices on BPD outcomes in these infants
- Presence of prenatal steroid administration
Time frame: 30 days
To assess the impact of steroid practices on BPD outcomes in these infants
- Administration of steroids to the infant
Time frame: 30 days
To determine if steroid use has an impact on infant growth
- Collect growth and calculate the z-score at five intervals
Time frame: 30 days
To determine if steroid use has an impact on NICU length of stay (LOS)
- NICU LOS in days
Time frame: 30 days
To determine if the average fluid intake in the first week of life influences the severity of BPD
- Fluid average from DOL 1-6
Time frame: 1-6 days
To determine if diuretic administration influences the severity of BPD
- If applicable, the DOL of first furosemide and/or chlorothiazide doses
Time frame: 1-6 days
Plan to share: No
Ran from Aug 2021 to primary completion in Sep 2022, 12 months.
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This study is completed, as verified in Nov 2024. You cannot join it, but the record below documents what was studied.
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Pediatrix