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CompletedNCT04967937Updated Jul 20, 2021

Neuromuscular Training Improves Single-Limb Stability

An interventional study of Strengthening, resistance exercise, plyometric and dynamic movement training in ACL Injury, sponsored by Riphah International University. Completed at 1 site in Pakistan. Open to female participants aged 13 Years to 20 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-07-20.

Sponsored by Riphah International University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 7 months after the study started (first participant enrolled Nov 2020, registered Jul 2021).
Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Not applicable
Ages
13 Years to 20 Years
Sex
Female
01

Study summary

Pretest/post-test study design, study will try to determine if a 6-week neuromuscular training program designed to decrease the incidence of anterior cruciate ligament (ACL) injuries would improve single-limb stability in young female athletes. Healthy female high school athletes will participate in this study. Single-limb postural stability for both lower extremities will be assessed with Stork balance test, Star Excursion Balance Test for Dynamic Balance and Single leg stance test for static balance. Participants will be included through convenient sampling. Informed consent will be taken from all the participants.

Read the detailed description

In this Controlled single-group pretest/post-test study design, study will try to determine if a 6-week neuromuscular training program designed to decrease the incidence of anterior cruciate ligament (ACL) injuries would improve single-limb stability in young female athletes. Current study hypothesized that neuromuscular training would result in an improvement of postural stability, with the greatest improvement taking place in the medial-lateral direction. Healthy female high school athletes will participate in this study. Single-limb postural stability for both lower extremities will be assessed with Stork balance test, Star Excursion Balance Test for Dynamic Balance and Single leg stance test for static balance. Participants will be included through convenient sampling. Informed consent will be taken from all the participants. Those individuals who will match the inclusion and exclusion criteria will be a part of the study. The neuromuscular training program will consist of three 90-minute training sessions per week for 6 weeks. Following the completion of the training program, each subject will be re-evaluated to determine change in total, anterior-posterior, and medial-lateral single-limb stability.

02

Conditions studied

  • ACL Injury

Keywords

  • Single limb stability
  • Neuromuscular Training
  • Female athletes
  • ACL
03

In context

Anterior Cruciate Ligament Injuries

512 studies on the registry are indexed under Anterior Cruciate Ligament Injuries; 164 are open to participants now.

This study's enrollment of 20 is below the median of 56 across 373 interventional studies indexed under Anterior Cruciate Ligament Injuries.

Browse Anterior Cruciate Ligament Injuries studies →

Lead sponsor

Riphah International University is the lead sponsor of 2,133 studies on the registry; 633 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
13 Years to 20 Years
Sexes eligible
Female
Accepts healthy volunteers
Yes

Inclusion criteria

  • Age will range from 13-20
  • Female participants
  • Individuals with Postural instability and Impaired balance will be included.

Exclusion criteria

Exclusion Criteria:

  • Any malignancy
  • Infection
  • Systemic illness
  • Trauma
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
20 participants (actual)

Study arms

  • Experimental
    Single-Group

    The neuromuscular training program will consist of three 90-minute training sessions per week for 6 weeks. The 3 components of the dynamic neuromuscular training protocol utilized in this study include: (1) balance training and hip/pelvis/trunk strengthening, (2) plyometrics and dynamic movement training, and (3) resistance training. Following the completion of the training program, each subject will be re-evaluated to determine change in total, anterior-posterior, and medial-lateral single-limb stability. Two-way analysis of variance models will be used to determine differences between pre-training and post-training and between limbs.

    Other: Strengthening, resistance exercise, plyometric and dynamic movement training

Interventions

  • OtherStrengthening, resistance exercise, plyometric and dynamic movement training

    (1) balance training and hip/pelvis/trunk strengthening, (2) plyometrics and dynamic movement training, and (3) resistance training.

06

What researchers measure

Primary outcomes

  1. i. Star Excursion Balance Test for Dynamic Balance

    dynamic test that requires strength, flexibility, and proprioception. It is a measure of dynamic balance that provides a significant challenge to athletes and physically active individuals. The test can be used to assess physical performance

    Time frame: 6th Week

Secondary outcomes

  1. ii. Single Limb Stance Test (Static Posture and Balance)

    The Single leg Stance (SLS) Test is used to assess static postural and balance control.Performed with eyes open and hands on the hips.Client must stand unassisted on one leg

    Time frame: 6th Week

Other outcomes

  1. iii. Stork balance test

    The standing stork test monitors the progress of the athletes' abilities to maintain balance in a static position. This test monitors the balance of athletes because the more balance you have as an athlete, the better you may perform on the field and the fewer injuries you are likely to sustain.

    Time frame: 6th Week

07

Study locations

1 site
  • Samnabad Sports complex
    Faisalābad, Punjab, Pakistan
08

References and documents

Publications

  • Etty Griffin LY. Neuromuscular training and injury prevention in sports. Clin Orthop Relat Res. 2003 Apr;(409):53-60. doi: 10.1097/01.blo.0000057788.10364.aa. PubMed 12671485 ↗
  • Richmond SA, Kang J, Doyle-Baker PK, Nettel-Aguirre A, Emery CA. A School-Based Injury Prevention Program to Reduce Sport Injury Risk and Improve Healthy Outcomes in Youth: A Pilot Cluster-Randomized Controlled Trial. Clin J Sport Med. 2016 Jul;26(4):291-8. doi: 10.1097/JSM.0000000000000261. PubMed 27367045 ↗
  • McLeod TC, Armstrong T, Miller M, Sauers JL. Balance improvements in female high school basketball players after a 6-week neuromuscular-training program. J Sport Rehabil. 2009 Nov;18(4):465-81. doi: 10.1123/jsr.18.4.465. PubMed 20108849 ↗
  • Gianotti SM, Marshall SW, Hume PA, Bunt L. Incidence of anterior cruciate ligament injury and other knee ligament injuries: a national population-based study. J Sci Med Sport. 2009 Nov;12(6):622-7. doi: 10.1016/j.jsams.2008.07.005. Epub 2008 Oct 2. PubMed 18835221 ↗
  • Viola RW, Steadman JR, Mair SD, Briggs KK, Sterett WI. Anterior cruciate ligament injury incidence among male and female professional alpine skiers. Am J Sports Med. 1999 Nov-Dec;27(6):792-5. doi: 10.1177/03635465990270061701. PubMed 10569367 ↗
  • Bonci CM. Assessment and evaluation of predisposing factors to anterior cruciate ligament injury. J Athl Train. 1999 Apr;34(2):155-64. PubMed 16558559 ↗
  • Hewett TE, Lindenfeld TN, Riccobene JV, Noyes FR. The effect of neuromuscular training on the incidence of knee injury in female athletes. A prospective study. Am J Sports Med. 1999 Nov-Dec;27(6):699-706. doi: 10.1177/03635465990270060301. PubMed 10569353 ↗
  • Myer GD, Ford KR, Brent JL, Hewett TE. Differential neuromuscular training effects on ACL injury risk factors in"high-risk" versus "low-risk" athletes. BMC Musculoskelet Disord. 2007 May 8;8:39. doi: 10.1186/1471-2474-8-39. PubMed 17488502 ↗
  • Chappell JD, Limpisvasti O. Effect of a neuromuscular training program on the kinetics and kinematics of jumping tasks. Am J Sports Med. 2008 Jun;36(6):1081-6. doi: 10.1177/0363546508314425. Epub 2008 Mar 21. PubMed 18359820 ↗
  • Hewett TE, Ford KR, Myer GD. Anterior cruciate ligament injuries in female athletes: Part 2, a meta-analysis of neuromuscular interventions aimed at injury prevention. Am J Sports Med. 2006 Mar;34(3):490-8. doi: 10.1177/0363546505282619. Epub 2005 Dec 28. PubMed 16382007 ↗
  • Ireland ML. Anterior cruciate ligament injury in female athletes: epidemiology. J Athl Train. 1999 Apr;34(2):150-4. PubMed 16558558 ↗
  • Myer GD, Sugimoto D, Thomas S, Hewett TE. The influence of age on the effectiveness of neuromuscular training to reduce anterior cruciate ligament injury in female athletes: a meta-analysis. Am J Sports Med. 2013 Jan;41(1):203-15. doi: 10.1177/0363546512460637. Epub 2012 Oct 9. PubMed 23048042 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 20, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04967937
Lead sponsor
Riphah International University
Responsible party
Sponsor
First posted
Jul 20, 2021
Start date
Nov 30, 2020
Primary completion
Apr 30, 2021
Completion
Jun 30, 2021
Last update
Jul 20, 2021

Study contacts

Syed Shakil Ur Rehman
principal investigator · Riphah International University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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