An interventional study of Parmigiano Reggiano and Whey Protein in Atrophy, Muscular, Aging and Inflammation, sponsored by University of Padova. Status unknown at 1 site in Italy. Open to participants aged 60 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-05-05.
Sponsored by University of Padova · Not applicable, Interventional, and Treatment
Aging is associated with the loss of muscle mass and function (sarcopenia) and reduced tissue regenerative capacity.
Eccentric exercise (ECC) is a model of RET that can be used with the elderly, due to the ability of the muscle to combine high muscle strength production with low energy cost. ECC contractions are significantly more damaging to the muscles and produce greater muscle strength, for these reasons there is a greater risk of inducing muscle damage before the muscle is able to adapt.
Parmigiano Reggiano (PR) has some peculiar bromatological characteristics. The proteins contained in it, and in particular the potentially bioactive peptide sequences, can rapidly provide the amino acids necessary to promote muscle growth and repair during exercise. Furthermore, PR can be an important source of fatty acids, of which a significant amount of short-chain fatty acids (SCFA) which are known to have important clinical effects on body composition and metabolic health and can have a systemic anti-inflammatory effect.
Therefore, the central hypothesize is that PR consumed while being engaged in a RET can provide more energy substrates and improve muscle recovery, redcue inflammatory markers and improve lipid metabolism. To date, no studies have studied its function on recovery from exercise nor in the elderly.
494 studies on the registry are indexed under Muscular Atrophy; 94 are open to participants now.
This study's planned enrollment of 24 is below the median of 33 across 335 interventional studies indexed under Muscular Atrophy.
Browse Muscular Atrophy studies →University of Padova is the lead sponsor of 210 studies on the registry; 42 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
participants will consume 50 g/die of the dietary supplement and undergo to eccentric exercise training 3 times/week
Dietary Supplement: Parmigiano Reggiano
participants will consume 20 g/die of the dietary supplement and undergo to eccentric exercise training 3 times/week
Dietary Supplement: Whey Protein
subjects will receive 50 g/die of the dietary supplement
subjects will receive 20 g/die of the dietary supplement
Leg lean Mass
kg of lean mass measured via DEXA
Time frame: Change from baseline to up to 12 weeks
inflammatory marker: IL-6
levels of plasma IL-6 (mg/dL)
Time frame: Change from baseline to up to 12 weeks
cholesterol
levels of plasma cholesterol (mg/dL)
Time frame: Change from baseline to up to 12 weeks
This study is status unknown, as verified in Jan 2021. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
University of Padova