ClinicalTrials.gg
Status unknownNCT04798300Updated Jun 18, 2021

Wear of Enamel Antagonist to Two Different Types of Monolithic Zirconia Monolithic Zirconia

An interventional study of Newly Introduced Gradient Monolithic Zirconia and Full Strength Monolithic Zirconia in Wear, Occlusal, sponsored by Cairo University. Status unknown. Open to participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-06-18.

Sponsored by Cairo University · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Jun 2021), so the status shown — last known as Not yet recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
26
Allocation
Randomized
Ages
18 Years to 50 Years
Sex
All
01

Study summary

The aim of the present study is to evaluate the wear of enamel opposed by Newly Introduced Gradient Monolithic Zirconia compared to that of enamel opposed by Full Strength Monolithic Zirconia

Read the detailed description

The aim of the present study is to evaluate the wear of enamel opposed by Newly Introduced Gradient Monolithic Zirconia compared to that of enamel opposed by Full Strength Monolithic Zirconia Teeth preparation and impressions, placement and permanent cementation of the final restoration using resin cement, and optical scanning of both the restoration and the opposing tooth. Follow up postoperatively after six and twelve months, and optical scanning of both the restoration and the opposing tooth.

02

Conditions studied

  • Wear, Occlusal

Browse trials for

03

In context

Tooth Attrition

14 studies on the registry are indexed under Tooth Attrition; 5 are open to participants now.

This study's planned enrollment of 26 is close to the median of 26 across 11 interventional studies indexed under Tooth Attrition.

Browse Tooth Attrition studies →

Lead sponsor

Cairo University is the lead sponsor of 4,941 studies on the registry; 1,458 are open to participants now.

Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

-

All subjects are required to be:

  1. From 18-50 years old, be able to read and sign the document.
  2. Have no active periodontal or pulpal diseases, have teeth with good restorations.
  3. Psychologically and physically able to withstand conventional dental procedures.
  4. Patients planned for a single coverage restoration in the posterior area.
  5. Patients with a natural (not crowned) opposing antagonist.
  6. Able to return for follow-up examinations and evaluation.

Exclusion criteria

Exclusion Criteria:

  • Patient less than 18 or more than 50 years 2. Patients with severe clenching or bruxing habits. 3. Patient with active resistant periodontal diseases 4. Patients with poor oral hygiene and uncooperative patients 5. Pregnant women 6. Patients in the growth stage with partially erupted teeth 7. Psychiatric problems or unrealistic expectations 8. Lack of opposing dentition at the area of interest. 9. Presence of dental prosthesis in the opposing arch at the area of interest.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
26 participants (estimated)

Study arms

  • Other
    tested material

    Newly Introduced Gradient Monolithic Zirconia (Intervention)

    Procedure: Newly Introduced Gradient Monolithic Zirconia

  • Active comparator
    comparator material

    Full Strength Monolithic Zirconia (Comparator)

    Procedure: Full Strength Monolithic Zirconia

Interventions

  • ProcedureNewly Introduced Gradient Monolithic Zirconia

    Fabrication of full-coverage crowns over posterior teeth using Newly Introduced Gradient Monolithic Zirconia to measure wear

  • ProcedureFull Strength Monolithic Zirconia

    Fabrication of full-coverage crowns over posterior teeth using Full Strength Monolithic Zirconia to measure wear

06

What researchers measure

Primary outcomes

  1. Enamel wear of teeth opposing the restorations to be tested opposing to tested restorations

    measured by Geomagic professional software

    Time frame: one year

Secondary outcomes

  1. Wear of restorations to tested opposed to natural teeth

    measured by Geomagic professional software

    Time frame: one year

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: Yes

Supporting information: Study protocol, Clinical study report

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 18, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04798300
Lead sponsor
Cairo University
Responsible party
Sara Ismail Mohamed Hussein (principle investigator, Cairo University) — Principal investigator
First posted
Mar 15, 2021
Start date
Sep 1, 2021 (estimated)
Primary completion
Sep 1, 2022 (estimated)
Completion
Sep 1, 2022 (estimated)
Last update
Jun 18, 2021

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jun 2021. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion