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Status unknownNCT04772599Updated Feb 26, 2021

Measurement of Noradrenaline Concentrations Using Different Dilution Methods

An observational study in Arterial Hypertension, sponsored by University Hospital, Strasbourg, France. Status unknown at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2021-02-26.

Sponsored by University Hospital, Strasbourg, France · Observational

The sponsor has not verified this record recently (last verified Feb 2021), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Other
Time perspective
Prospective
Enrollment
50
Ages
18 Years and older
Sex
All
01

Study summary

Norepinephrine is the vasopressor of choice for the treatment of peri-anesthetic arterial hypotension. The use of this drug at significantly lower concentrations (dilution factor between 40 and 200) than the commercial preparation is increasingly common in the operating room ("baby-noradrenaline").

In addition, dilution errors are potentially serious for the patient (hypertensive peak) The preparation of precise dilutions is an important factor for the safe use of this medically In this study, the investigators wish to compare the dilution method of the protocol with another method of preparation (left to the free choice of the participant).

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Conditions studied

  • Arterial Hypertension

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Keywords

  • Noradrenaline
  • Norepinephrine
  • Concentration of noradrenaline
  • Vasopressor
  • Baby-noradrenaline
  • Dilution of Noradrenaline
03

In context

Hypertension

6,689 studies on the registry are indexed under Hypertension; 965 are open to participants now.

This study's planned enrollment of 50 is below the median of 210 across 1,359 observational studies indexed under Hypertension.

Browse Hypertension studies →

Lead sponsor

University Hospital, Strasbourg, France is the lead sponsor of 966 studies on the registry; 342 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Sampling method
Probability sample

Study population

Employee of the University Hospitals of Strasbourg accepting to participate in the study

Inclusion criteria

  • Adult person,
  • Employee of Strasbourg University Hospitals,
  • Likely to have to prepare anesthesia drugs in the operating room (intern, hospital student, IADE, IADE student)

Exclusion criteria

Exclusion criteria:

  • Subject's refusal to participate in the study
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Study design

Observational model
Other
Time perspective
Prospective
Enrollment
50 participants (estimated)
Patient registry
No
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What researchers measure

Primary outcomes

  1. Measurement of noradrenaline concentrations using different dilution methods

    Measurement methods: * High performance liquid chromatography * Measurement of the concentration of noradrenaline in the biochemical laboratory of the University Hospitals of Strasbourg

    Time frame: 1 hour after the preparation of the noradrenaline solutions

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Study locations

1 of 1 sites recruiting
  • Strasbourg University Hospitals - Anesthesia-intensive care unit
    Strasbourg, 67091, France
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 26, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04772599
Lead sponsor
University Hospital, Strasbourg, France
Responsible party
Sponsor
First posted
Feb 26, 2021
Start date
Feb 21, 2021
Primary completion
Jul 1, 2021 (estimated)
Completion
Jul 1, 2021 (estimated)
Last update
Feb 26, 2021

Study contacts

Thiên-Nga CHAMARAUX-TRAN, MD
Contact
ThienNga.CHAMARAUX-TRAN@chru-strasbourg.fr
33 3 88 12 70 75
Saïd CHAYER, PhD, HDR
Contact
said.chayer@chru-strasbourg.fr
33 3 88 11 66 90

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Feb 2021. You cannot join it, but the record below documents what was studied.

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Discussion

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