A Phase 4 interventional study of paracetamol and Placebo in Impacted Third Molar Tooth, sponsored by Melaka Manipal Medical College. Completed at 1 site in Malaysia. Open to participants aged 21 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-02-24.
Sponsored by Melaka Manipal Medical College · Phase 4, Interventional, and Supportive care
The purpose of the study is to evaluate the efficacy of pre-emptive paracetamol in reducing intra operative pressure and post operative pain after surgical removal of impacted mandibular third molar using visual analogue scale
Melaka Manipal Medical College is the lead sponsor of 10 studies on the registry; none are open to participants now.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
ASA physical status
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Paracetamol
Drug: paracetamol
placebo
Drug: Placebo
tablet paracetamol 500 mg
Also known as: Paracetamol 500 mg
placebo
intraoperative pain
A 10 mm Visual Analogue Scale with higher score depicting severe pain
Time frame: during luxation of tooth
postoperative pain
A 10 mm Visual analogue scale with higher score depicting severe pain
Time frame: 1 day
Time to rescue medication
minutes
Time frame: upto 360 minutes
number of patients taking rescue medications
Total number of patients taking rescue medications
Time frame: Upto 360 minutes
Plan to share: Yes
Supporting information: Study protocol, Statistical analysis plan
No publications or documents are linked to this record.
This study is completed, as verified in Feb 2021. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Acetaminophen
Melaka Manipal Medical College