An interventional study of closure of wound using n- butyl 2-octyl cyanoacrylate tissue adhesive and closure of wound using braided silk suture in Wound Heal, sponsored by Melaka Manipal Medical College. Completed at 1 site in Malaysia. Open to participants aged 17 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-04-06.
Sponsored by Melaka Manipal Medical College · Not applicable, Interventional, and Treatment
This study compares the effectiveness of two materials used for intraoral wound closure after removal of impacted mandibular third molar tooth. One Group received braided black silk suture and the other group received N-butyl 2-octyl cyanoacrylate tissue adhesives.
Conventional method of wound closure after removal of impacted mandibular molar is by suturing the wound using braided black silk suture and allowing for primary healing. Suturing in the most posterior region of oral cavity is not easy, it requires more time and additional skills as well. Patient has to come for a second visit for removal of suture. Moreover tight sutures may lead to ischemia and necrosis.
Tissue adhesives adopts the idea of sutureless wound closure. They are even sloughed off from the surface of mucosa 7 days after the application.
This study compares the effectiveness of conventional sutures and tissue adhesives in closure of intraoral surgical wounds after removal of mandibular third molar.
Melaka Manipal Medical College is the lead sponsor of 10 studies on the registry; none are open to participants now.
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Exclusion Criteria:
Application of cyanoacrylate tissue adhesive over the surgical wound
Procedure: closure of wound using n- butyl 2-octyl cyanoacrylate tissue adhesive
Suturing the surgical wound using braided black silk
Procedure: closure of wound using braided silk suture
Application of cyanoacrylate tissue adhesives over the surgical wound
suturing the surgical wound using braided black silk
Postoperative pain
A 10 mm Numerical rating scale assessing postoperative pain. Possible score ranges from 0 (no pain) to 10 (worst possible pain).
Time frame: 1st postoperative day
postoperative pain
A 10 mm Numerical rating scale assessing postoperative pain. Possible score ranges from 0 (no pain) to 10 (worst possible pain).
Time frame: 2nd postoperative day
Postoperative pain
A 10 mm Numerical rating scale assessing postoperative pain. Possible score ranges from 0 (no pain) to 10 (worst possible pain).
Time frame: 3rd postoperative day
Postoperative pain
A 10 mm Numerical rating scale assessing postoperative pain. Possible score ranges from 0 (no pain) to 10 (worst possible pain).
Time frame: 4th postoperative day
postoperative pain
A 10 mm Numerical rating scale assessing postoperative pain. Possible score ranges from 0 (no pain) to 10 (worst possible pain).
Time frame: 5th postoperative day
wound healing
A 5 point early wound healing scale assessing wound healing after 7 postoperative days.
Time frame: 7th postoperative day
Plan to share: Yes
Supporting information: Study protocol
Time frame: 1 month
Access criteria: Study protocol will be provided only if requested through a proper channel, dean of college , with proper justification.
No publications or documents are linked to this record.
Ran from Mar 2020 to primary completion in Apr 2021, 12 months.
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This study is completed, as verified in Apr 2023. You cannot join it, but the record below documents what was studied.
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Melaka Manipal Medical College