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CompletedNCT04746326Updated Feb 9, 2021

Treatment in Right Colon Diverticulitis Patients

An interventional study of Failure conservative treatment and Surgery in Outcome, sponsored by Tepecik Training and Research Hospital. Completed at 1 site in Turkey. Per ClinicalTrials.gov, last updated 2021-02-09.

Sponsored by Tepecik Training and Research Hospital · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
26
Allocation
Non-randomized
Sex
All
01

Study summary

The right colon diverticula, unlike those in the left colon, contain all layers of the colon and is called the true diverticulum. Perforation is observed less frequently due to its full thickness. Conservative treatment can be applied unless complications such as abscess formation and free perforation occur. Unlike the left, right colon diverticulitis has low complications and can be treated conservatively. The differential diagnosis of right colon diverticulitis should be kept in mind in order to prevent unnecessary surgeries. Surgical treatment is inevitable in cases such as recurrent diverticulitis, generalized peritonitis, and suspected malignancy.

Read the detailed description

The right colon diverticula, unlike those in the left colon, contain all layers of the colon and is called the true diverticulum. Perforation is observed less frequently due to its full thickness. Conservative treatment can be applied unless complications such as abscess formation and free perforation occur. Here, we aimed to discuss the results of conservative and surgical treatment for right colon diverticulitis in the light of the literature. 150 patients treated for colon diverticulitis between 2015-2020 were retrospectively screened. Right colon diverticulitis detected incidentally, missing data, and left colon diverticulitis were excluded from the study. Data of a total of 26 patients were accessed. Unlike the left, right colon diverticulitis has low complications and can be treated conservatively. The differential diagnosis of right colon diverticulitis should be kept in mind in order to prevent unnecessary surgeries. Surgical treatment is inevitable in cases such as recurrent diverticulitis, generalized peritonitis, and suspected malignancy

02

Conditions studied

  • Outcome

Keywords

  • diverticulum
  • surgery
  • appendicitis
  • sigmoid volvulus
  • caecum
  • diverticulitis
03

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • diagnosed with right colon diverticulitis

Exclusion criteria

Exclusion Criteria:

  • Left colon diverticulitis
  • Right colon diverticulitis detected incidentally
  • lacking data
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
26 participants (actual)

Study arms

  • Other
    Conservative treatment

    Conservative treatment stopping oral intake, intravenous antibiotic therapy.

    Other: Conservative treatment

  • Other
    Operative treatment

    Operative procedure Right hemicolectomy Wedge resection of cecum Diverticulectomy + appendectomy Diverticulectomy Appendectomy + drainage

    Procedure: Failure conservative treatment · Procedure: Surgery

Interventions

  • ProcedureFailure conservative treatment

    Surgery was performed in patients who failed conservative treatment.

  • ProcedureSurgery

    Surgery was performed in patients who had generalized peritonitis and perforation.

  • OtherConservative treatment

    Conservative treatment was performed in patients who had no generalized peritonitis and perforation.

05

What researchers measure

Primary outcomes

  1. Number of Participants with mortality

    mortality

    Time frame: up to 24 weeks

  2. Number of Participants with wound infection

    wound infection

    Time frame: up to 24 weeks

06

Study locations

1 site
  • Tepecik Training and Research Hospital
    İzmir, 35180, Turkey
07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT04746326
Lead sponsor
Tepecik Training and Research Hospital
Responsible party
Semra Demirli Atici (Primary investigator, Tepecik Training and Research Hospital) — Principal investigator
First posted
Feb 9, 2021
Start date
Jan 1, 2020
Primary completion
Jan 1, 2021
Completion
Jan 20, 2021
Last update
Feb 9, 2021

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Feb 2021. You cannot join it, but the record below documents what was studied.

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