An observational study in Familial Mediterranean Fever, sponsored by Medipol University. Completed at 1 site in Turkey. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-08-02.
Sponsored by Medipol University · Observational
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Among 20 studies in Familial Mediterranean Fever with a site in Turkey — 7 open to participants now, 8 under way, none of them phase 3. Familial Mediterranean Fever · Turkey.
Among the 20 studies in Familial Mediterranean Fever with a site in Turkey, this one is the 6th largest by enrollment of the 10 observational ones that give a count, is one of 2 that started in 2018, is one of 10 observational ones, and was the 6th registered.
61 studies on the registry are indexed under Familial Mediterranean Fever; 27 are open to participants now.
Browse Familial Mediterranean Fever studies →7 of the 20 studies in Familial Mediterranean Fever with a site in Turkey are open now. Recruiting first, the newest first:
R-Pharm International, LLC · Sites in Turkey, Armenia, Russian Federation
Ages 18–80
Istanbul University · Sites in Turkey
Ages 8–18
Istanbul University - Cerrahpasa · Sites in Turkey
Ages 12–18
Istanbul University - Cerrahpasa · Sites in Turkey
Ages 12–18 · Healthy volunteers
Aysima Barlak · Sites in Turkey
Ages 18+
A study can be open while its sites in Turkey have not opened yet or have stopped. Only those recruiting at a site in Turkey →
Of the 12 Familial Mediterranean Fever studies recruiting now, 4 (33%) set no upper age limit and 5 (42%) stop at 75 or younger; 10 take children under 18; 3 take healthy volunteers.
This study: 18 Years to 65 Years · all sexes · healthy volunteers too.
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20 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 1 · Phase 2 4 · Phase 3 1 · Phase 4 1
First in 2001; this study’s year is marked. 2 started in 2018.
By drug class, each counting the studies that test any of its medicines:
This study's enrollment of 60 is below the median of 89 across 30 observational studies indexed under Familial Mediterranean Fever.
Median enrollment 60 across the 10 interventional studies, 80 across the 10 observational. Of the 10 that completed or were terminated, 0 (0%) have results posted.
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5 of 20 have an industry lead sponsor. The 10 most frequent:
Medipol University is the lead sponsor of 326 studies on the registry; 86 are open to participants now.
Medipol University has 1 study filed under Familial Mediterranean Fever — fewer than ten, so there is no comparison to draw.
1 of the studies in Familial Mediterranean Fever with a site in Turkey that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06830213Aysima BarlakInvestigation of the Validity, Reliability and Responsiveness of the BETY-BQ in FMF | 2027-03-30 |
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Among the 20 studies in Familial Mediterranean Fever with a site in Turkey, from their registry updates:
Nothing recorded among them since 2026-09-25.
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Motor imagery is the mental representation of movement without any doing body movement. A main function of imagery is to aid the self-regulation of thoughts, feelings, and behaviours. Studies have shown to be more effective for individuals displaying a higher level of imagery ability when using imagery to improve motor and motivational outcomes, including self-efficacy. The aim of this study is to measure the movement imagery ability in patients with Familial Mediterranean Fever and compare it with healthy individuals.
Familial Mediterranean Fever (FMF) is an autosomal recessive disease characterized by recurrent and self-limited attacks of fever associated with abdominal, chest, and joint pain. Previous studies have shown that individuals with FMF are more limited in terms of physical function than the normal population, and depression and anxiety are more common in these individuals. Being a lifetime disease, quality of life, and mental health can be affected due to serious complications such as attack frequency, disease resistance, and sometimes amyloidosis. Mental imagery is the ability to imaging the movement without doing the physical execution of the movement. During the last years, mental imagery is used in clinical practice as a tool for the treatment of chronic pain. Pain differs in patients with rheumatic diseases. Stress is one of the predictors of pain in patients with FMF. Even if the frequency is variable when attacks happen they may affect patients physically and their mental health and the ability to cope. A main function of imagery is to aid the self-regulation of thoughts, feelings, and behaviors. To use imagery for motor and motivational outcomes firstly the imagery ability levels should be measured.
Patients with Familial Mediterranean Fever and Healthy Controls
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Exclusion Criteria:
30 participants
Behavioral: movement imagery ability
30 participants
Behavioral: movement imagery ability
Determining the movement imagery ability: internal visual, external visual and kinesthetic imagery
Movement Imagery Questionnaire-3 (MIQ-3)
It is a questionnaire containing 12 items to evaluate the visual imagination skills of the individual. It evaluates internal visual imagery, external visual imagery, and kinesthetic imagery. For each item, first of all, individuals read the description of the movement, and then it is desired to perform the movement physically and after that, the same movement is requested. Individuals evaluate the degree of imagination on a 7-point Likert-type scale ranging from 1 (very difficult to see/feel) to 7 (very easy to see/feel). The motion visualization questionnaire has good psychometric properties, internal reliability, and estimated validity.
Time frame: Baseline
McGill Melzack Pain Questionnaire (MPQ)
MPQ consists of 78 descriptors grouped into four categories: sensory, affective, evaluative, and miscellaneous. These four categories were grouped into 20 subclasses each made up of 2 to 6 words according to pain intensity. Patients were asked to choose the pain descriptors according to the type of pain they felt during the attack episodes. Patients were instructed to choose one of the words that best described their type of pain experience. Changing of pain with time was assessed. Pain right now, pain at its worst and pain at its least was evaluated. Pain exacerbating or relieving factors were recorded.
Time frame: Baseline
Pain Catastrophizing Scale
Pain Catastrophizing Scale identifies catastrophic thoughts or feelings and ineffective coping strategies of patients. PCS is a Likert-type self-assessment scale consisting of thirteen items. Each item is evaluated between 0 and 4 points. The total score ranges from 0 to 52. Includes rumination, magnification, and helplessness subscales. High scores indicate that the level of disaster is high.
Time frame: Baseline
Plan to share: Undecided
Ran from Jan 2018 to primary completion in Feb 2021, 37 months.
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This study is completed, as verified in Aug 2022. You cannot join it, but the record below documents what was studied.
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Familial Mediterranean Fever →