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CompletedNCT04722016LUDREUpdated Jan 26, 2021

LUNG ULTRASONOGRAPHY DECREASES RADIATION EXPOSURE

An observational study in Newborn Rds, Transient Tachypnea of the Newborn and Pneumonia, sponsored by Hacettepe University. Completed at 1 site in Turkey. Open to participants aged Up to 2 Days. Per ClinicalTrials.gov, last updated 2021-01-26.

Sponsored by Hacettepe University · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
104
Ages
Up to 2 Days
Sex
All
01

Study summary

We aimed to decrease in the number of chest X-rays in newborns with respiratory distress, with the use of lung ultrasonography.

From January 2019 to June 2020, 104 newborn infants with respiratory distress enrolled in this study. We used bed side ultrasound as the first line tecnique for lung imaging. X-ray were taken in cases with increasing respiratory distress in spite of treatment according to diagnosis depending on USG findings. We calculated decreased number of chest X-ray for every patient and evaluated the estimated decrease in radiation exposure.

Read the detailed description

Background:

Chest X-ray is commonly used as first line imaging method to diagnose the reason of respiratory distress in NICUs. Lung ultrasound is a new diagnostic tool for lung imaging, and this method has been used more common recently in NICUs.

Objectives:

We aimed to determine the decrease in the number of chest X-rays in newborns with respiratory distress, with the use of lung ultrasonography.

Methods:

From January 2019 to June 2020, 104 newborn infants with respiratory distress enrolled in this study. We used bed side ultrasound as the first line tecnique for lung imaging. X-ray were taken in cases with increasing respiratory distress in spite of treatment according to diagnosis depending on USG findings. We calculated decreased number of chest X-ray for every patient and evaluated the estimated decrease in radiation exposure.

02

Conditions studied

  • Newborn Rds
  • Transient Tachypnea of the Newborn
  • Pneumonia

Keywords

  • lung ultrasonography
  • chest x ray
  • newborn
03

In context

Tachypnea

39 studies on the registry are indexed under Tachypnea; 4 are open to participants now.

Browse Tachypnea studies →

Lead sponsor

Hacettepe University is the lead sponsor of 983 studies on the registry; 212 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Up to 2 Days
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Term or preterm neonates with respiratory distress that started within the first 24 h after birth

Inclusion criteria

  • Term or preterm neonates with respiratory distress that started within the first 24 h after birth were included if they showed at admission signs of respiratory distress defined as: tachypnea (respiratory rate >60 breaths/min), intercostal/subcostal retractions, grunting, or FiO2 requirement >0.21.

Exclusion criteria

Exclusion Criteria:

  • Patients with a diagnosis of major malformations or chromosomal abnormalities, inherited metabolic diseases, congenital muscle disease-hypotonicity, hypoxic ischemic encephalopathy were not enrolled.
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
104 participants (actual)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Reduced radiation exposure

    We aimed to decrease in the number of chest X-rays in newborns with respiratory distress, with the use of lung ultrasonography.

    Time frame: 18 months

07

Study locations

1 site
  • Hacettepe University
    Ankara, 06230, Turkey
08

References and documents

Publications

  • Escourrou G, De Luca D. Lung ultrasound decreased radiation exposure in preterm infants in a neonatal intensive care unit. Acta Paediatr. 2016 May;105(5):e237-9. doi: 10.1111/apa.13369. No abstract available. PubMed 26880491 ↗
  • Tandircioglu UA, Yigit S, Oguz B, Kayki G, Celik HT, Yurdakok M. Lung ultrasonography decreases radiation exposure in newborns with respiratory distress: a retrospective cohort study. Eur J Pediatr. 2022 Mar;181(3):1029-1035. doi: 10.1007/s00431-021-04296-5. Epub 2021 Oct 23. PubMed 34687334 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 26, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04722016
Lead sponsor
Hacettepe University
Responsible party
H. Tolga Çelik (associate professor, Hacettepe University) — Principal investigator
First posted
Jan 25, 2021
Start date
Jan 1, 2019
Primary completion
Jun 1, 2020
Completion
Jun 1, 2020
Last update
Jan 26, 2021

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2021. You cannot join it, but the record below documents what was studied.

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