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Status unknownNCT04677725NEATUpdated Nov 3, 2022

NEtwork to Control ATherothrombosis (NEAT Registry)

An observational study in Coronary Artery Disease, Peripheral Arterial Disease and Atherothrombosis, sponsored by Hospital do Coracao. Status unknown at 1 site in Brazil. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2022-11-03.

Sponsored by Hospital do Coracao · Observational

The sponsor has not verified this record recently (last verified Nov 2022), so the status shown — last known as Active, not recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
2,000
Ages
18 Years and older
Sex
All
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Study summary

NEAT is an observational cohort (Prospective registry of real world data) of patients with coronary and peripheral artery disease in an outopatient setting.

Read the detailed description

National multicenter registry in Brazil with initial plan of 25 sites from the 5 Brazilian regions. It will be coordinated by HCOR Research Institute which will perform regulatory, data and site management beyond academic leadership.NEAT is an observational cohort (Prospective registry of real world data) of patients with coronary and peripheral artery disease in an outopatient setting with 12 months of follow-up with collection of data at baseline, 6 months and 12 months.

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Conditions studied

  • Coronary Artery Disease
  • Peripheral Arterial Disease
  • Atherothrombosis
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In context

Coronary Artery Disease

5,598 studies on the registry are indexed under Coronary Artery Disease; 957 are open to participants now.

This study's planned enrollment of 2,000 is above the median of 336 across 1,947 observational studies indexed under Coronary Artery Disease.

Browse Coronary Artery Disease studies →

Lead sponsor

Hospital do Coracao is the lead sponsor of 66 studies on the registry; 14 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients with coronary and peripheral arterial disease in an outpatient setting

Inclusion criteria

Patients ≥45 years followed in ambulatory setting with ≥1 of the following 3 criteria:

  1. Documented coronary disease (≥1 criteria must apply):

    • Stable angina
    • History of Unstable Angina
    • History of coronary angioplasty/stenting
    • History of coronary artery bypass graft
    • Myocardial infarction within the last 20 years
  2. Documented symptomatic Peripheral Arterial Disease (≥1 criteria must apply):

    • Previous aorto-femoral bypass surgery, limb bypass surgery, or percutaneous transluminal angioplasty revascularization of the iliac, or infra-inguinal arteries, or
    • Previous limb or foot amputation for arterial vascular disease, or
    • History of intermittent claudication and one or more of the following: 1) An ankle/arm blood pressure (BP) ratio \< 0.90, or 2) Significant peripheral artery stenosis (≥50%) documented by angiography, or by duplex ultrasound.

Exclusion criteria

Exclusion Criteria:

  • Patients from institutions that don't provide the Institutional Authorization Term,
  • Incapacity of follow-up in one year according to investigator judgment (severe neuropsychiatric condition, life expectancy \< 12 months)
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
2,000 participants (estimated)
Target follow-up
12 Months
Patient registry
Yes
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What researchers measure

Primary outcomes

  1. Percentage of patients receiving evidence based therapies to reduce cardiovascular risk

    DOMAIN 1: Appropriate use of antithrombotic therapy

    Time frame: Baseline

  2. Percentage of patients receiving evidence based therapies to reduce cardiovascular risk

    DOMAIN 2: Cholesterol control

    Time frame: Baseline

  3. Percentage of patients receiving evidence based therapies to reduce cardiovascular risk

    DOMAIN 3: Blood pressure control

    Time frame: Baseline

  4. Percentage of patients receiving evidence based therapies to reduce cardiovascular risk

    DOMAIN 4: Glycemic control / diabetes treatment

    Time frame: Baseline

  5. Percentage of patients receiving evidence based therapies to reduce cardiovascular risk

    DOMAIN 5: Weight control

    Time frame: Baseline

  6. Percentage of patients receiving evidence based therapies to reduce cardiovascular risk

    DOMAIN 6: Non-pharmacological intervention: In this domain, there are 2 items to be evaluated: 1) No smoking; 2) Physical exercise ≥ 150 minutes per week.

    Time frame: Baseline

Secondary outcomes

  1. Percentage of patients receiving complete evidence based therapies to reduce cardiovascular risk

    Patient should receive all of the following to consider complete evidence based therapy: Appropriate use of antithrombotic therapy; Cholesterol control; Blood pressure control; Glycemic control / diabetes treatment; Weight control; Non-pharmacological intervention

    Time frame: 6 and 12 months

  2. Percentage of patients with complete control of risk factors (blood pressure, cholesterol and glycemia)

    blood pressure, cholesterol and glycemia levels at baseline, 06 and 12 months

    Time frame: baseline, 06 and 12 months

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Study locations

1 site
  • Hospital Do Coração
    São Paulo, SP 05410001, Brazil
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 3, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04677725
Lead sponsor
Hospital do Coracao
Collaborators
Bayer
Responsible party
Sponsor
First posted
Dec 21, 2020
Start date
Sep 30, 2020
Primary completion
Mar 2023 (estimated)
Completion
Apr 2023 (estimated)
Last update
Nov 3, 2022

Study contacts

Pedro de Barros e Silva, MD, MHS, PhD
principal investigator · Faculty

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Nov 2022. You cannot join it, but the record below documents what was studied.

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