An interventional study of Anodal tDCS and sham tDCS in Fatigue and Stroke, sponsored by University College, London. Completed at 1 site in United Kingdom. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2020-11-18.
Sponsored by University College, London · Not applicable, Interventional, and Basic science
This is a double-blind, sham-controlled, anodal tDCS study to understand the effect of increasing motor cortex excitability on post-stroke fatigue.
7,286 studies on the registry are indexed under Stroke; 2,007 are open to participants now.
This study's enrollment of 33 is below the median of 50 across 5,369 interventional studies indexed under Stroke.
Browse Stroke studies →University College, London is the lead sponsor of 632 studies on the registry; 145 are open to participants now.
Of its 6 completed or terminated interventional studies of FDA-regulated products, 2 (33%) have results posted.
Counted across the registry records on this site, refreshed daily.
Diagnosed with stroke at least 3 months post-stroke
Exclusion Criteria:
Other neurological conditions on Anti-depressants severe motor impairment (affected hand grip \<60% unaffected hand) severe cognitive impairment (unable to follow instructions, or give informed consent) scored >11 in the depression sub-section of HADS questionnaire contraindications for TMS or tES
40 minutes of 2mA intensity direct current stimulation
Device: Anodal tDCS
40 minutes of 0mA intensity. the session starts with a ramp up to 2mA, but machine is switched off after 2 minutes of stimulation.
Device: sham tDCS
40 minutes of 2mA intensity direct current stimulation was delivered over both the right and left motor cortex simultaneously
The stimulator was switched off after 2 minutes of stimulation.
Fatigue Severity Scale - 7
a questionnaire based fatigue scale
Time frame: 2 weeks
Resting Motor Threshold
This is a measure of cortical excitability as measured by transcranial magnetic stimulation
Time frame: 1 day
Input-output curves
This is a measure of cortical recruitment as measured by transcranial magnetic stimulation
Time frame: 1 day
Perceived effort - Explicit
A VAS scale associated with a grip task
Time frame: 1 day
Perceived effort - Implicit
A novel line length estimation task
Time frame: 1 day
This study is completed, as verified in Nov 2020. You cannot join it, but the record below documents what was studied.
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University College, London