An interventional study of Metrics-driven quality improvement (MDQI) in Opioid-use Disorder and Substance Use Disorders, sponsored by NYU Langone Health. Completed at 4 sites in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-07-15.
Sponsored by NYU Langone Health · Not applicable, Interventional, and Health services research
This project will develop and test quality measures for and a facilitation model to help addictions treatment clinics increase use of medicines for opioid use disorders, retain clients longer in care, and help more people move into successful recovery. At the end of the project, we will have developed specific training and coaching protocols as well as electronic clinical support tools to guide quality improvement that can be disseminated within New York and the rest of the country.
The study will test a clinic-level intervention that uses external facilitators to provide guidance to addictions clinics and contain three key components: 1) training on data driven management; 2) training and guidance on patient-centered care and OUD medication; and 3) electronic tools for shared decision making and patient progress monitoring.
There will be 4 sources of data examined in this study: 3 at the patient level and 1 at the staff level. The sources of patient data include: 1) State administrative data from all clients receiving treatment at the enrolled clinics (\~7,950); 2) a subsample (1,200) who will be recruited directly from the clinics to complete patient-reported outcome assessments, and 3) treatment progress data for clients will also be collected.
For our administrative source of data, a final study population of approximately 7,950 individuals who are receiving treatment in the 30 enrolled outpatient treatment clinics for OUD is anticipated. Clinics will be located in the New York City metropolitan region (including Nassau, Westchester, and Rockland counties) and the Capital Region (including Albany, Rensselaer, Saratoga, Montgomery, Schenectady, and Schoharie counties). Staff at each enrolled clinic will also be interviewed and surveyed.
1,411 studies on the registry are indexed under Opioid-Related Disorders; 290 are open to participants now.
This study's enrollment of 7,950 is above the median of 63 across 1,123 interventional studies indexed under Opioid-Related Disorders.
Browse Opioid-Related Disorders studies →NYU Langone Health is the lead sponsor of 1,391 studies on the registry; 254 are open to participants now.
Of its 227 completed or terminated interventional studies of FDA-regulated products, 191 (84%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Behavioral: Metrics-driven quality improvement (MDQI)
The intervention broadly consists of training and coaching to clinic staff and leadership on 1) clinical quality measure monitoring; 2) clinical practice process change management; and 3) use of tools for shared decision making and patient treatment progress monitoring.
Change in clinic-level rates of initiation to OUD medications
Time frame: Assessed from commencement of the trial in Year 1 of the study to the conclusion of the trial in Year 4 of the study.
Change in clinic-level rates of adherence to OUD medications
Time frame: Assessed from commencement of the trial in Year 1 of the study to the conclusion of the trial in Year 4 of the study.
Retention in Care
Clinic rates of 6-month client retention in care
Time frame: Assessed from commencement of the trial in Year 1 of the study to the conclusion of the trial in Year 4 of the study.
Change in Incidence of Overdoses
Time frame: Assessed from commencement of the trial in Year 1 of the study to the conclusion of the trial in Year 4 of the study.
Change in Incidence of Substance Use-Related Hepatitis C Infection
Time frame: Assessed from commencement of the trial in Year 1 of the study to the conclusion of the trial in Year 4 of the study.
Change in Number of Emergency Room Visits
Time frame: Assessed from commencement of the trial in Year 1 of the study to the conclusion of the trial in Year 4 of the study.
Change in Health Status
Change in health status is measured by the first item of the SF-12 Health Survey: "In general, would you say your health is: 1 - excellent, 2 - very good, 3 - good, 4 - fair, 5 - poor". Scores range from 1-5, with a higher score indicating worse health.
Time frame: Assessed from the start of each clinic in the intervention to 1 year post-intervention
Cost of treatment
Cost of the intervention to the clinic
Time frame: Assessed from commencement of the intervention at each clinic to 1 year post-intervention
Change in clinic-level rates of clients with Severe OUD
As indicated by daily use and/or injection drug use as indicated in state administrative admission data
Time frame: Assessed from commencement of the intervention at each clinic to 1 year post-intervention
Change in clinic level-rates of clients identified as homeless
As indicated in state administrative admission data
Time frame: Assessed from commencement of the intervention at each clinic to 1 year post-intervention
Change in clinic-rates of clients with co-existing psychiatric disorder as indicated in state administrative admission data
Time frame: Assessed from commencement of the intervention at each clinic to 1 year post-intervention
Plan to share: Yes — Individual participant data that underlie the results reported in this article resulting from surveys only, after deidentification (text, tables, figures, and appendices), will be available. Client outcome data from State administrative data files will not be available for sharing due to the nature of the data security agreements.
Supporting information: Study protocol, Sap
This study is completed, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.
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