A Phase 4 interventional study of RegenLab PRP and hyaluronic acid in PRP, ACL and Hyaluronic Acid, sponsored by Kaohsiung Veterans General Hospital.. Status unknown at 1 site in Taiwan. Open to participants aged 20 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-10-14.
Sponsored by Kaohsiung Veterans General Hospital. · Phase 4, Interventional, and Treatment
Purpose: The purpose of this article is to examine the clinical application of PRP and PRP+hyaluronic acid in disorders in the knee.
Methods:
The study was conducted on 150 adult patients with age over 20 years old affected by unilateral ACL complete tear and receiving ACL reconstruction. We divided the patients in three groups, and we treated the group A with perioperative injection of HHA, group B with perioperative HHA+PRP, group C with perioperative normal saline.
Follow-up:
Every 1,3,and 12months, we recheck physical exmianation at OPD and recheck MRI at postoperative 3 months.
512 studies on the registry are indexed under Anterior Cruciate Ligament Injuries; 163 are open to participants now.
This study's planned enrollment of 150 is above the median of 56 across 372 interventional studies indexed under Anterior Cruciate Ligament Injuries.
Browse Anterior Cruciate Ligament Injuries studies →Kaohsiung Veterans General Hospital. is the lead sponsor of 102 studies on the registry; 12 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Intraoperative1 kit of Platelet-rich plasma(PRP) injection into knee joint after anterior cruciate ligament (ACL) reconstruction.
Combination Product: RegenLab PRP
Intraoperative1 kit of PRP+Hyaluronic acid(HA) injection into knee joint after ACL reconstruction.
Combination Product: hyaluronic acid
Intraoperative 20 ml normal saline injection into knee joint after ACL reconstruction.
Other: normal saline
PRP preparations also improved functional outcome scores compared to hyaluronic acid and placebo in patients affected by knee osteoarthritis (OA). Based on previous studys, we can conclude that the PRP treatment is a safe and efficacious procedure which can provide functional benefit.
Few studies investigated the effects of HA+PRP combined treatment for knee osteoarthritis (OA). Numerous studies demonstrated the efficacy of HA injection therapy in knee OA for a clinical point of view, reducing the pain and improving the quality of life.
Also known as: RegenLab PRP
In this study, we compare introperative PRP/PRP+HA/normal saline in ACL reconstruction patient.
150 of participants with preoperative and postoperative physical examination are accessed by anterior drawer test and Lachman test
the investigators recheck physical exmianation of participants at OPD; physical examination was checked by one orthopedist
Time frame: postoperative 1 month
150 of participants with preoperative and postoperative physical examination are accessed by anterior drawer test and Lachman test
the investigators recheck physical exmianation of participants at OPD; physical examination was checked by one orthopedist
Time frame: postoperative 3 months
150 of participants with preoperative and postoperative physical examination are accessed by anterior drawer test and Lachman test
the investigators recheck physical exmianation of participants at OPD; physical examination was checked by one orthopedist
Time frame: postoperative 12 months
150 of participants with preoperative and postoperative Magnetic Resonance Imaging are accessed
anterior cruciate ligament was accessed by MRI T1 and T2 image; MRI was checked by one orthopedist
Time frame: postoperative 3 month
This study is status unknown, as verified in Oct 2020. You cannot join it, but the record below documents what was studied.
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Anterior Cruciate Ligament Injuries→
Kaohsiung Veterans General Hospital.