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CompletedNCT04554290Updated Oct 24, 2023

Giant Cell Arteritis and Differential Diagnoses Associated With Positive Temporal Artery Biopsy

An observational study in Giant Cell Arteritis and Vasculitis, sponsored by Central Hospital, Nancy, France. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2023-10-24.

Sponsored by Central Hospital, Nancy, France · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
114
Ages
18 Years and older
Sex
All
01

Study summary

Temporal artery biopsy is a useful tool helping to the diagnosis of giant cell arteritis. However, other diagnoses might be associated with abnormal temporal artery biopsy. The purpose of this study is to describe the frequency of giant cell arteritis differential diagnoses with positive temporal artery biopsy.

02

Conditions studied

  • Giant Cell Arteritis
  • Vasculitis

Keywords

  • giant cell arteritis
  • temporal artery biopsy
  • vasculitis
03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

all patients with significant inflammation on temporal artery biospy, with a final diagnosis of giant cell arteritis or an other diagnosis.

Inclusion criteria

  • positive artery biopsy between january 1st 2000 and july 25th 2019

Exclusion criteria

Exclusion Criteria:

  • orther vascular biopsy than temporal artery biospy
04

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
114 participants (actual)
Patient registry
No

Groups and cohorts

  • positive temporal artery biopsy

    all adult patients with significant inflammation shown on temporal artery biopsy

    Diagnostic Test: temporal artery biopsy

Interventions

  • Diagnostic testtemporal artery biopsy

    description of temporal artery biopsy features, and its correlation with diagnosis of giant cell arteritis or other differential diagnoses.

05

What researchers measure

Primary outcomes

  1. percentage of giant cell arteritis and differential diagnoses

    Time frame: baseline

06

Study locations

1 site
  • Nancy University Hospital
    Nancy, Lorraine 54500, France
07

References and documents

Publications

  • Pontille F, Decker P, Gauchotte G, Jaussaud R, Moulinet T. Diagnoses associated with temporal arteritis. Eur J Intern Med. 2023 Nov;117:140-143. doi: 10.1016/j.ejim.2023.08.010. Epub 2023 Aug 14. No abstract available. PubMed 37586985 ↗
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Registry details

Key details

Study ID
NCT04554290
Lead sponsor
Central Hospital, Nancy, France
Responsible party
Thomas MOULINET (MD, Central Hospital, Nancy, France) — Principal investigator
First posted
Sep 18, 2020
Start date
Aug 1, 2020
Primary completion
Mar 30, 2021
Completion
Dec 30, 2022
Last update
Oct 24, 2023

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Oct 2023. You cannot join it, but the record below documents what was studied.

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