An interventional study of injectable PRF in Root Resorption, sponsored by Fayoum University. Completed at 1 site in Egypt. Open to participants aged 13 Years to 30 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-10-08.
Sponsored by Fayoum University · Not applicable, Interventional, and Treatment
Currently Endodontics looks forward for regeneration rather than repair. Regenerative endodontic therapy was limited to pulp revascularization of necrotic pulp in immature teeth , followed by mature teeth. Recently pulp revascularization technique by induction of blood clot was applied in the treatment of inflammatory root resorption. So far, no clinical study for management of teeth with inflammatory internal root resorption by using injectable PRF revascularization has been described in the literature. Thus, this is the first clinical attempt to manage inflammatory root resorption in necrotic incisor teeth using injectable PRF regenerative approach.
13 teeth in a total of 10 patients with inflammatory root resorption will be treated using revascualrization technique, iPRF will be prepared and unjected in the canal after previous canal disinfection with calcium hydroxide for 2-4 weeks. cBCT will be taken preoperative and 12 month follow up period, also clinical and radiographic follow uo will be considered every 3 months for 1 year.
43 studies on the registry are indexed under Root Resorption; 9 are open to participants now.
This study's enrollment of 10 is below the median of 29 across 36 interventional studies indexed under Root Resorption.
Browse Root Resorption studies →Fayoum University is the lead sponsor of 148 studies on the registry; 44 are open to participants now.
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Exclusion Criteria:
Biological: injectable PRF
blood sample and centrifuged to obtain i-PRF
change in volumetric size of internal root resorption lesions
Measuring volumetric dimensions of resorption lesion pre and postoperatively using CBCT
Time frame: 12 months
change in volumetric size of periapical lesions
Measuring volumetric dimensions of periapical lesion pre and postoperatively using CBCT
Time frame: 12 months
This study is completed, as verified in Oct 2021. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: P-prf