ClinicalTrials.gg
SuspendedNCT04339530Updated May 10, 2021

Vitamin D and Type 2 Diabetes Risk in UK Adults

An observational study in Overweight and Obesity, sponsored by Liverpool Hope University. Suspended at 1 site in United Kingdom. Open to participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-05-10.

Primary conditionObesityRegistry: OverweightReclassifiedWhy we changed it
Registry
Overweight — the first condition term the registry derived for this study.
ClinicalTrials.gg
Obesity
Why
  1. The study's listed conditions name Obesity, a narrower term within Overweight.
Confidence
High: the new condition is named in the study's own listed conditions. Of 351 hand-checked studies reclassified this way, 68% were exactly right and 84% in the right disease family; the registry's first term was right for 5% (measured 2026-10-21). How we classify →
Wrong?
Tell us the study's main condition →

Sponsored by Liverpool Hope University · Observational

Why this study was suspended
This study is suspended until further notice. Recruitment should resume when COVID-19 safety restrictions are lifted.
Study type
Observational
Model
Other
Time perspective
Cross-sectional
Enrollment
300
Ages
18 Years to 50 Years
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 452 studies in Obesity with a site in United Kingdom — 92 open to participants now, 126 under way, 39 of them phase 3. Obesity · United Kingdom.

Planned enrollment
31st of 81
300 · median 130
Started
2019
with 24 others
Observational
81 of 452
24 open now
Registered
251st of 452
by date

Among the 452 studies in Obesity with a site in United Kingdom, this one is the 31st largest by planned enrollment of the 81 observational ones that give a count, is one of 25 that started in 2019, is one of 81 observational ones, and was the 251st registered.

Obesity

11,522 studies on the registry are indexed under Obesity; 2,033 are open to participants now.

Browse Obesity studies →

Open to participants now

92 of the 452 studies in Obesity with a site in United Kingdom are open now. Recruiting first, the newest first:

87 more — sign in →

All 92 open studies →

A study can be open while its sites in United Kingdom have not opened yet or have stopped. Only those recruiting at a site in United Kingdom →

Who these studies take

Of the 1,336 Obesity studies recruiting now, 377 (28%) set no upper age limit and 856 (64%) stop at 75 or younger; 168 take children under 18; 491 take healthy volunteers.

This study: 18 Years to 50 Years · all sexes · healthy volunteers too.

The full table on the hub →

This tab as a report to print or save as PDF → With an account.

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Watch this landscapeDownload CSVNarrow it in search →With an account: a weekly mail of what changed among 452 studies in Obesity with a site in United Kingdom, or all of them as a file.
02

Study summary

This study is exploring the association between vitamin D and Type 2 diabetes risk in normal weight and overweight UK adults.

Read the detailed description

The aim of this study is to assess the link between vitamin D status and glucose homeostasis in a population of normal weight and overweight individuals (BMI> 18.5 Kg/m2).

03

Conditions studied

  • Overweight
  • Obesity

Browse trials for

Keywords

  • Vitamin D
  • Type 2 diabetes
  • Insulin resistance
  • Glucose
04

In context

Obesity Reclassified

11,522 studies on the registry are indexed under Obesity; 2,033 are open to participants now.

This study's planned enrollment of 300 is above the median of 114 across 2,154 observational studies indexed under Obesity.

Browse Obesity studies →

Lead sponsor

Liverpool Hope University is the lead sponsor of 6 studies on the registry; 1 is open to participants now.

Compared within Obesity, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Overweight. The counts are of registry records indexed under each term, refreshed daily. How we classify →

05

Who can participate

Ages eligible
18 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

Overweight and obese adults , aged 18-50 (premenopausal women), males and females with no known chronic conditions.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Normal weight and overweight and obese adults (>= 18.5 Kg/m2) with no restriction to ethnicity, occupation or socioeconomic status.
  • Males and females
  • 18-50 years

Exclusion criteria

Exclusion Criteria:

  • Patients diagnosed with diabetes type 2, myocardial infarction or coronary heart disease.
  • > 6.4%
  • Pregnancy
  • Diagnosis of liver disease (including liver enzymes > 3 times above normal values)
  • Diagnosis of renal disease (creatinine of > 150 mmol/l)
  • women
Terms in these criteria, in plain language(3)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

BMI (body mass index)

Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.

What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.

HbA1c

A blood test of average blood sugar over the past two to three months, given as a percentage or in mmol/mol. 6.5% (48 mmol/mol) or more is the usual threshold for diabetes, normally confirmed by a second test.

Postmenopausal

Periods have stopped for good: usually no period for 12 months in a row without another medical reason, sometimes confirmed by a blood test (FSH).

06

Study design

Observational model
Other
Time perspective
Cross-sectional
Enrollment
300 participants (estimated)
Patient registry
No

Interventions

  • OtherNormal weight and overweight adults

    Association between vitamin D levels and insulin resistance

07

What researchers measure

Primary outcomes

  1. HOMA-IR (Homeostasis modelling assessment-Insulin resistance)

    A venous blood sample collected for the measurement of insulin and glucose levels.

    Time frame: One venous sample collected after 8 hours of fasting

Secondary outcomes

  1. Fasting bood glucose levels

    A venous blood sample collected for the measurement of glucose levels

    Time frame: One venous sample collected after 8 hours of fasting

  2. HbA1C

    Fingerprick sample

    Time frame: Sample collected at one single time point with no follow-up

  3. Body fat percentage

    Body fat percentage measured through DEXA

    Time frame: Measurement conducted in the morning after 8 hours of fasting

  4. Central and brachial Systolic and Diastolic Blood pressure

    Blood pressure measured using a digital sphygmomanometer

    Time frame: Measurement taken 3 times after a-10 minute rest

  5. Augmentation index

    Arterial stiffness assessment test

    Time frame: Measurement taken 3 times after a-10 minute rest

08

Study locations

1 site
  • School of Health sciences
    Liverpool, L1 9JD, United Kingdom
09

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

10

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Started Jul 2019 (actual). Primary completion is estimated for Jul 2022, 36 months after the start.

How these figures are worked out, and which studies are left out of them.

Registered
Apr 3, 2020
First posted
Apr 9, 2020
StartActual
Jul 1, 2019
Primary completionEst.
Jul 1, 2022
CompletionEst.
Jul 1, 2022
Last update
May 10, 2021
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on May 10, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
11

Registry details

Key details

Study ID
NCT04339530
Lead sponsor
Liverpool Hope University
Responsible party
Grace Farhat (Principal Investigator, Liverpool Hope University) — Principal investigator
First posted
Apr 9, 2020
Start date
Jul 1, 2019
Primary completion
Jul 1, 2022 (estimated)
Completion
Jul 1, 2022 (estimated)
Last update
May 10, 2021

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is suspended, as verified in May 2021. You cannot join it, but the record below documents what was studied.

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Discussion

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