An interventional study of Raspberries in Inflammation and Insulin Resistance, sponsored by Pennington Biomedical Research Center. Completed. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2020-03-12.
Sponsored by Pennington Biomedical Research Center · Not applicable, Interventional, and Prevention
Red raspberries (Rubus idaeus) are a good source of health enhancing hydrolyzable and condensed tannins, flavonoids, anthocyanins, phenolic acids, rheosmin, potassium, carotenoids, vitamin C, and vitamin K1. Compared to other berries commonly consumed in the US, the health benefits of red raspberries to improve pre-diabetes mellitus (PDM) and type 2 diabetes have never been explored. The clinical study proposed in this project seeks to investigate the protective effect of whole red raspberries against insulin resistance, oxidative stress, and inflammation in PDM and type 2 diabetic patients. The in vitro study proposed in the project will assist in identifying the molecular mechanisms by which whole red raspberry protect islet cells against oxidative stress, insulin resistance and loss of cell function.
1,960 studies on the registry are indexed under Insulin Resistance; 306 are open to participants now.
This study's enrollment of 9 is below the median of 40 across 1,536 interventional studies indexed under Insulin Resistance.
Browse Insulin Resistance studies →Pennington Biomedical Research Center is the lead sponsor of 277 studies on the registry; 29 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Single serving smoothies drink made with red raspberries to be consumed daily for two weeks
Other: Raspberries
Red raspberry smoothies drink
Homeostatic Model Assessment for Insulin Resistance (HOMA-IR)
Ratio of fasting insulin and glucose
Time frame: 2 weeks
A high-sensitivity C-reactive protein (hs-CRP) measured in milligrams per liter
Measure of systemic inflammation
Time frame: 2 weeks
3,4-Dihydroxyphenylacetic acid (DOPAC) measured in nanograms per milliliter
Measure of systemic inflammation
Time frame: 2 weeks
No study locations are listed for this record.
Plan to share: Yes — Excel spreadsheets containing clinical trial data can be made available to other researchers after publication of research results.
Supporting information: Study protocol, Sap, Icf, Csr
No publications or documents are linked to this record.
This study is completed, as verified in Mar 2020. You cannot join it, but the record below documents what was studied.
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Pennington Biomedical Research Center