An interventional study of Exercise Blood Flow Restriction training and SHAM Exercise Blood Flow Restriction training in ACL Injury, sponsored by Mayo Clinic. Completed at 1 site in United States. Open to participants aged 13 Years to 40 Years. Per ClinicalTrials.gov, last updated 2023-02-03.
Sponsored by Mayo Clinic · Not applicable, Interventional, and Supportive care
Researchers are trying to find out whether the use of low-intensity strength exercises during the 2 weeks before surgery, and while the blood flow to the leg is reduced, will improve the outcomes after surgery to repair an injured ligament of the knee.
512 studies on the registry are indexed under Anterior Cruciate Ligament Injuries; 164 are open to participants now.
This study's enrollment of 29 is below the median of 56 across 373 interventional studies indexed under Anterior Cruciate Ligament Injuries.
Browse Anterior Cruciate Ligament Injuries studies →Mayo Clinic is the lead sponsor of 3,218 studies on the registry; 670 are open to participants now.
Of its 445 completed or terminated interventional studies of FDA-regulated products, 313 (70%) have results posted.
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Exclusion Criteria:
Subjects previously diagnosed with a torn ACL who have yet to undergo surgical reconstruction and pre-operative rehabilitation will do a series of low-intensity strength exercises while the blood flow to the leg is reduced by a blood flow restriction cuff.
Behavioral: Exercise Blood Flow Restriction training
Subjects previously diagnosed with a torn ACL who have yet to undergo surgical reconstruction and pre-operative rehabilitation will do a series of low-intensity strength exercises while a blood flow restriction cuff is applied but inflation pressure will be limited
Behavioral: SHAM Exercise Blood Flow Restriction training
While exercising, an Inflatable cuff, similar to a blood pressure cuff, is applied to the proximal aspect of the femur of the affected lower extremity inflated to occlude blood flow
While exercising Inflatable cuff, similar to a blood pressure cuff, applied to the proximal aspect of the femur of the affected lower extremity with limited inflation pressure to not occlude blood flow
Change in muscle diameter (hypertrophy)
Measured using ultrasound images of the musculature and soft tissue of the quadriceps femoris
Time frame: 2 weeks pre-operative, 8-10 days post-operative
Change in muscle strength
Muscle strength will be measured in subjects as the percent strength of the injured leg compared to the non-injured leg based on handheld dynamometer and the number of leg presses performed at the 1-rep maximum
Time frame: 2 weeks pre-operative, 4 weeks pre-operative, 8 weeks post-operative
Plan to share: No
This study is completed, as verified in Feb 2023. You cannot join it, but the record below documents what was studied.
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Anterior Cruciate Ligament Injuries→
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