An observational study in Multiple Sclerosis, sponsored by Universidad de Granada. Status unknown at 1 site in Spain. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-02-05.
Sponsored by Universidad de Granada · Observational
Multiple sclerosis is a chronic and highly disabling disorder with considerable social impact and economic consequences. It is caused by damage to the myelin sheath, the protective covering that surrounds nerve cells. Different areas are affected, including upper airway function, trunk motor control and cardiorespiratory performance. The aim of this study was to determinate the relevance of trunk motor control in upper airway function and cardiorespiratory performance in patients with multiple sclerosis.
3,460 studies on the registry are indexed under Multiple Sclerosis; 661 are open to participants now.
This study's planned enrollment of 60 is below the median of 100 across 1,016 observational studies indexed under Multiple Sclerosis.
Browse Multiple Sclerosis studies →Universidad de Granada is the lead sponsor of 241 studies on the registry; 41 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Inclusion Criteria:
Exclusion Criteria:
Exclusion Criteria:
Trunk motor control
The impairment of trunk motor control was measured with the Modified Trunk Impairment Scale (mTIS). The values range to 0 from 16 being higher values, better trunk motor control.
Time frame: baseline
Swallowing function
To evaluate swallowing function we used two questionnaires: the Swallowing quality of life questionnaire (SWAL-QOL). It contains 44 items and each item was scored from zero (the worst state) to four (the best state).
Time frame: baseline
Swallowing function
To evaluate swallowing function we used two questionnaires: the Eating Assessment Tool-10 (EAT-10). The values range from 0 to 4 being higher values worse swallowing function.
Time frame: baseline
Ventilation function
Ventilation capacity was measured with spirometry and peak flow using Spirobank II (MIR, Italy).
Time frame: baseline
Phonation function
The phonatory function and it´s repercussion on daily life was evaluated by the Voice handicap index (VHI-30),
Time frame: baseline
The exercise capacity focussed on lower limbs
The Five-Times-Sit-to-Stand test (5STS)
Time frame: baseline
The exercise capacity focussed on upper limbs
The exercise capacity focussed on upper limbs was measured by the unsupported upper-limb exercise test (UULEX)
Time frame: baseline
The anaerobic threshold
Incremental sit-to-stand test (ISTS)
Time frame: baseline
Psychological status
Psychological status was evaluated with and the Beck Depression Inventory (Beck) to measure depression. The values range to 0 from 63, being higher values, most severe depression.
Time frame: baseline
Psychological status
Psychological status was evaluated with the Beck Anxiety Inventory (BAI) to measure anxiety. The values range to 0 from 63, being higher values, most severe anxiety.
Time frame: baseline
The degree of neurological functioning
The degree of neurological functioning in patients with MS was measured with the Kurtzke Expanded Disability Status Scale (EDSS). The values range to 0 from 10, being 0 normal status healthy and 10 the death.
Time frame: baseline
The impact of the multiple sclerosis disease
The impact of the disease was determinate with the Multiple Sclerosis Impact Scale (MSIS-29). It´s an instrument with 20 physical items and 9 psychological items.
Time frame: baseline
This study is status unknown, as verified in Jan 2020. You cannot join it, but the record below documents what was studied.
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Universidad de Granada