An observational study in Disorder of Consciousness, Minimally Conscious State and FDG-PET, sponsored by Hangzhou Normal University. Completed at 1 site in China. Open to participants aged 16 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-07-08.
Sponsored by Hangzhou Normal University · Observational
Recently introduced hybrid PET/MR scanners provide the opportunity to measure simultaneously, and in direct spatial correspondence, both metabolic demand and functional activity of the brain, hence capturing complementary information on the brain's physiological state. Here we exploited PET/MR simultaneous imaging to explore the relationship between the metabolic information provided by resting-state fluorodeoxyglucose-PET (FDG-PET) and fMRI (rs-fMRI) in patients with disorders of consciousness.
290 studies on the registry are indexed under Consciousness Disorders; 109 are open to participants now.
This study's enrollment of 24 is below the median of 79 across 95 observational studies indexed under Consciousness Disorders.
Browse Consciousness Disorders studies →Hangzhou Normal University is the lead sponsor of 22 studies on the registry; 1 is open to participants now.
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Distinguishing patients in unresponsive wakefulness syndrome, UWS [i.e. patients showing eyes opening but no behavioral evidence of consciousness ] from patients in minimally conscious state, MCS [i.e., patients showing minimal, inconsistent but clearly discernible intentional behaviors ] is pivotal for decision making in the entire care pathway of patients with DoC.
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Exclusion Criteria:
Diagnostic Test: Multimodal Neuroimaging
fludeoxyglucose (FDG-)PET/MR imaging
resting-state fMRI
Use resting-state fMRI to test the functional connectivity
Time frame: Within 7 days
fludeoxyglucose (FDG-)PET
UseFDG-PET to test the metabolism.
Time frame: Within 7 days
This study is completed, as verified in Jul 2022. You cannot join it, but the record below documents what was studied.
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Hangzhou Normal University