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CompletedNCT04135950Updated Nov 20, 2025

Prospective Registry of Anterior Cruciate Ligament Reconstructions

An observational study in Anterior Cruciate Ligament Tear, Meniscal Tear and Cartilage Injury, sponsored by State University of New York at Buffalo. Completed at 1 site in United States. Per ClinicalTrials.gov, last updated 2025-11-20.

Sponsored by State University of New York at Buffalo · Observational

Study type
Observational
Model
Other
Time perspective
Prospective
Enrollment
1,646
Sex
All
01

Study summary

The purpose of the study is to investigate factors that are associated with outcomes of injury to the anterior cruciate ligament (ACL) in the knee among patients who are undergoing surgical reconstruction. This study is a registry of all patients having knee surgery at our institution performed by 4 fellowship-trained orthopaedic surgeons. The surgeon documents patient information on standard data forms including risk factors and surgical findings.

02

Conditions studied

  • Anterior Cruciate Ligament Tear
  • Meniscal Tear
  • Cartilage Injury
  • Bone Bruising
03

In context

Anterior Cruciate Ligament Injuries

512 studies on the registry are indexed under Anterior Cruciate Ligament Injuries; 164 are open to participants now.

This study's enrollment of 1,646 is above the median of 92 across 127 observational studies indexed under Anterior Cruciate Ligament Injuries.

Browse Anterior Cruciate Ligament Injuries studies →

Lead sponsor

State University of New York at Buffalo is the lead sponsor of 287 studies on the registry; 65 are open to participants now.

Of its 19 completed or terminated interventional studies of FDA-regulated products, 15 (79%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

All patients at our institution who are having ACL surgery by one of 4 fellowship-trained surgeons will be included in this registry.

Inclusion criteria

  • Patients undergoing ACL surgery

Exclusion criteria

Exclusion Criteria:

  • Previous surgery on the affected knee
  • Posterior cruciate ligament injuries
  • Grade 2 lateral collateral ligament or medial collateral ligament injuries
05

Study design

Observational model
Other
Time perspective
Prospective
Enrollment
1,646 participants (actual)
Target follow-up
20 Years
Patient registry
Yes
06

What researchers measure

Primary outcomes

  1. additional injury

    At the time of ACL surgery, it is determined if the patient has any other injuries to the meniscus or cartilage.

    Time frame: intraoperatively

07

Study locations

1 site
  • UBMD Orthopaedics and Sports Medicine
    Buffalo, New York 14226, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 20, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT04135950
Lead sponsor
State University of New York at Buffalo
Responsible party
Leslie Bisson (June A. and Eugene R. Mindell, MD Professor and Chair, State University of New York at Buffalo) — Principal investigator
First posted
Oct 23, 2019
Start date
Jan 2005
Primary completion
Oct 28, 2025
Completion
Oct 28, 2025
Last update
Nov 20, 2025

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2025. You cannot join it, but the record below documents what was studied.

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