ClinicalTrials.gg
CompletedNCT04121650Updated Jun 15, 2026

Executive Function and Symptom Reduction in Youth Receiving Home-based Treatment With Collaborative Problem Solving

An observational study in Child Behavior, Problem Behavior and Executive Dysfunction, sponsored by Massachusetts General Hospital. Completed at 1 site in United States. Open to participants aged 7 Years to 14 Years. Per ClinicalTrials.gov, last updated 2026-06-15.

Primary conditionProblem BehaviorRegistry: Child BehaviorReclassifiedWhy we changed it
Registry
Child Behavior — the first condition term the registry derived for this study.
ClinicalTrials.gg
Problem Behavior
Why
  1. The study's listed conditions name Problem Behavior, a narrower term within Child Behavior.
Confidence
High: the new condition is named in the study's own listed conditions. Of 351 hand-checked studies reclassified this way, 68% were exactly right and 84% in the right disease family; the registry's first term was right for 5% (measured 2026-10-21). How we classify →
Wrong?
Tell us the study's main condition →

Sponsored by Massachusetts General Hospital · Observational

Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
54
Ages
7 Years to 14 Years
Sex
All
01

Study summary

In this project, the investigators will extend prior results of parent-reported executive function growth and symptom reduction in children receiving home-based treatment with the Collaborative Problem Solving treatment approach (CPS), with a particular focus on examining children who have attention deficit hyperactivity disorder (ADHD). The investigators will examine executive functioning (EF) of children who are receiving CPS, measuring EF with parent-report and objective computer-based tasks, at two timepoints: at the start of treatment and approximately four months later, and will collect symptoms at these plus three additional timepoints: at discharge, 6-months after discharge, and 12-months after discharge.

02

Conditions studied

  • Child Behavior
  • Problem Behavior
  • Executive Dysfunction

Keywords

  • Executive Functioning
  • ADHD
  • Behavior Problems
  • Youth
  • CPS
  • Collaborative Problem Solving
  • Disruptive Behavior
  • Parenting
03

In context

Problem Behavior Reclassified

178 studies on the registry are indexed under Problem Behavior; 47 are open to participants now.

This study's enrollment of 54 is close to the median of 53 across 12 observational studies indexed under Problem Behavior.

Browse Problem Behavior studies →

Lead sponsor

Massachusetts General Hospital is the lead sponsor of 2,586 studies on the registry; 447 are open to participants now.

Of its 222 completed or terminated interventional studies of FDA-regulated products, 168 (76%) have results posted.

Compared within Problem Behavior, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Child Behavior. The counts are of registry records indexed under each term, refreshed daily. How we classify →

04

Who can participate

Ages eligible
7 Years to 14 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

The participants of this study are youth (ages 7 to 14) who are the identified clients being seen in home-based therapy at identified Youth Villages sites in Massachusetts.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Clients of participating non-profit organization that are receiving home-based youth mental health care
  • Speaking and writing English at level necessary to complete study requirements

Exclusion criteria

Exclusion Criteria:

  • Youth is in full state custody and consent cannot be obtained by a guardian
  • Youth and/or guardians do not speak English well enough to complete standardized measures
  • Youth has a confirmed or suspected Full Scale IQ below 70, or carries a prior diagnosis of Autism Spectrum Disorder at the moderate or severe level
05

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
54 participants (actual)
Patient registry
No

Interventions

  • BehavioralCollaborative Problem Solving

    CPS is an approach for understanding and reducing challenging behavior in youth. Under CPS, caregivers are taught to understand and identify the specific neurocognitive skill deficits that underlie their child's challenging behavior. Then the caregivers are taught to interact with the child in a way that solves chronic behavior problems while building the lagging neurocognitive skills to avoid future problems.

    Also known as: CPS

06

What researchers measure

Primary outcomes

  1. Change in Behavioral Symptoms

    Strengths and Difficulties Questionnaire (Parent-report measuring child emotional problems, conduct issues, hyperactivity/inattention, peer relationship problems, and pro- social behavior)

    Time frame: Baseline, 4 months, discharge, 6 months post-discharge, and 12 months post-discharge

  2. Change in Behavioral Symptoms

    Clinical Global Impressions (Measures clients' symptom severity, global improvement, and therapeutic response)

    Time frame: Baseline, 4 months, and discharge

  3. Change in Executive Functioning Skills

    Behavior Rating Inventory of Executive Functioning (Parent-report measuring deficits in different domains of executive functioning)

    Time frame: Baseline and 4 months

  4. Change in Executive Functioning Skills

    CANTAB computer-based cognitive tasks (Motor Screening Task, Stop Signal Task, Spatial Span, Multitasking Test, Stockings of Cambridge, Intra-Extra Dimensional Set Shift)

    Time frame: Baseline and 4 months

Secondary outcomes

  1. Change in Child-Parent Relationship

    Child-Parent Relationship Scale (A 15-question measure of parents perceptions of their relationship with their child by using a scale of 1-5 where 1 "definitely does not apply" and a 5 "definitely applies to the child-parent relationship")

    Time frame: Baseline and 4 months

  2. Treatment providers' fidelity to Collaborative Problem Solving (as a moderator)

    CPS Treatment Integrity Rating Form Short (Observational ratings by trained CPS coaches that quantitatively measure providers' fidelity to the practice of the CPS treatment approach)

    Time frame: provider rating made closest in proximity to four-month timepoint

07

Study locations

1 site
  • Massachusetts General Hospital
    Boston, Massachusetts 02114, United States
08

References and documents

Study documents

PDFs hosted by the registry, ClinicalTrials.gov.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 15, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04121650
Collaborators
Gerstner Philanthropies, Youth Villages
Responsible party
Alisha R Pollastri (Director of Research and Evaluation, Think:Kids, Massachusetts General Hospital) — Principal investigator
First posted
Oct 10, 2019
Start date
Oct 14, 2019
Primary completion
Jul 1, 2022
Completion
Jul 1, 2022
Last update
Jun 15, 2026

Study contacts

Alisha R Pollastri, Ph.D.
principal investigator · Massachusetts General Hospital

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion