Problem Behavior clinical trials
The registry lists 178 studies for Problem Behavior across more than 10 countries. 47 are recruiting or about to start. 104 of them are mainly about Problem Behavior (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Who runs them
Karolinska Institutet (7) · Yale University (6) · Rutgers, The State University of New Jersey (4) · Accare (4) · New York University (3) · Vanderbilt University (3) · Johns Hopkins Bloomberg School of Public Health (3) · Wayne State University (3)
What is being tested here
Drugs under test in Problem Behavior studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Propranolol | 1 | 0 | 1 |
| Pitolisant | 1 | 1 | 1 |
| Aripiprazole | 0 | 2 | 3 |
| Prazosin | 0 | 0 | 1 |
| Medical Marijuana | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Apr 2027A Study of Pitolisant in Patients With Prader-Willi Syndrome · Phase 3 · Harmony Biosciences Management, Inc.
- Nov 2026A Randomized Controlled Trial on Brief Behavioral Parent Training · Accare
- Nov 2026Effectiveness of School-Based Solution Focused Brief Therapy for Academic and Behavioral Problems in Adolescents · National University of Modern Languages
- Dec 2026Parent-Educator Action Response · Ann & Robert H Lurie Children's Hospital of Chicago
- Dec 2026Cognitive-Behavioral Therapy for Irritability in Children With Autism Spectrum Disorder and Intellectual Disability · Yale University
- Dec 2026Parent-Child Interaction Therapy (PCIT) for Children With Traumatic Brain Injury (TBI): A Stepped-Care Model · University of Miami
- Dec 2026A Mobile App to Improve 24-Hour Movement Guideline Adherence in Preschoolers · University of Kansas Medical Center
- Dec 2026Effects and Implementation of a Brief Version of Parent-Child Interaction Therapy · Karolinska Institutet
- Dec 2026Testing the Impact of the Parenting Young Children Check-up · Wayne State University
- Dec 2026Examining the Impact of the Parenting Young Children Check-up · Wayne State University
Who these studies take
Of the 36 Problem Behavior studies recruiting now, 9 (25%) set no upper age limit and 26 (72%) stop at 75 or younger. 28 (78%) take children under 18. 2 (6%) are for women only and 0 (0%) for men only; 18 (50%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 17 (47%) | 17 (47%) |
| 18 | 14 (39%) | 14 (39%) |
| 30 | 14 (39%) | 12 (33%) |
| 40 | 14 (39%) | 12 (33%) |
| 50 | 14 (39%) | 12 (33%) |
| 65 | 11 (31%) | 11 (31%) |
| 75 | 10 (28%) | 10 (28%) |
| 85 | 10 (28%) | 10 (28%) |
Across all 178 studies, recruiting or not: 70% stop at 75 or younger and 69% at 65; 81% take children; 2% are for women only and 2% for men only; 45% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Problem Behavior studies take
Of 112 interventional studies with no phase under Problem Behavior, half reached primary completion within 24 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 24 mo13–51 · 112 studies | — | 24 mo13–51 · 111 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting1
- Improving Student Mental Health Through a Universal Trauma-Informed InterventionOct 19, 2026NCT07842432
Newly registered2
- Study of Psychoeducation and Reading for Kids (SPARK)Nov 6, 2026NCT07922876
- Hybrid Pilot of Personalized Parent-Child Interaction TherapyOct 21, 2026NCT07887295
Studies
Recruiting first, then most recently updated. Showing 50 of 178. Browse all 178 → or search them.
- Study of Psychoeducation and Reading for Kids (SPARK)Not yet recruitingNCT07922876Not applicable1 country
- Hybrid Pilot of Personalized Parent-Child Interaction TherapyNot yet recruitingNCT07887295Not applicable1 country
- Effectiveness of School-Based Solution Focused Brief Therapy for Academic and Behavioral Problems in AdolescentsRecruitingNCT07811648Not applicable1 country
- Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With AutismRecruitingNCT07091279Phase 21 country
- Future Leaders Program: Testing a Youth Leadership, Engagement, and Mindfulness ProgramRecruitingNCT06736522Not applicable1 country
- A Study of Pitolisant in Patients With Prader-Willi SyndromeRecruitingNCT06366464Phase 313 countries
- This Study Aims to Evaluate the Cultural Adaptation, Implementation, and Effectiveness of the RAISE Program Grounded in Malti's 3 E's Model and the Kindness Developmental Paradigm in PortugalNot yet recruitingNCT07759531Not applicable
- Testing the Impact of the Parenting Young Children Check-upRecruitingNCT07750054Early Phase 11 country
- Behavioral Parent Training to Address Early Childhood Disruptive Behavior Using the DOCS Parenting ProgramsRecruitingNCT07505381Not applicable1 country
- A Randomized Controlled Trial on Brief Behavioral Parent TrainingRecruitingNCT05591820Not applicable1 country
- Examining the Impact of the Parenting Young Children Check-upRecruitingNCT07734545Early Phase 11 country
- Effects of an SMS-Based Parenting Intervention on Anxiety Symptoms in Preschool ChildrenNot yet recruitingNCT07728344Not applicable
- Assessment of Language Comprehension and Learning in Children Attending Child Psychiatry Services (TICOALA-SOINS)RecruitingNCT07283458Not applicable1 country
- Executive Function and Parenting in ChildhoodRecruitingNCT06241300Not applicable1 country
- LOVING (Learning About Our Behavior is Valuable for Increasing Nurturing Relationships and Healthy Growth) RCTRecruitingNCT07687524Not applicable1 country
- Evaluation of the Invest in Play Program - a New Parent Intervention for Children With Problem BehaviorRecruitingNCT06984809Not applicable1 country
- Reducing Blood Pressure in Mid-life Adult Binge DrinkersRecruitingNCT05522075Not applicable1 country
- Brief Behavioral Teacher Training for Behavioral DifficultiesRecruitingNCT06127030Not applicable1 country
- Exploration of Acceptability of Alcohol InterventionsNot yet recruitingNCT075803781 country
- Parent-Child Interaction Therapy (PCIT) for Children With Traumatic Brain Injury (TBI): A Stepped-Care ModelNot yet recruitingNCT06193382Not applicable1 country
- Manualized Assessment and Treatment Model of Challenging BehaviorRecruitingNCT05928247Not applicable1 country
- Cognitive-Behavioral Therapy for Irritability in Children With Autism Spectrum Disorder and Intellectual DisabilityEnrolling by invitationNCT02914951Not applicable1 country
- Feasibility and Acceptability of Internet-based Parent-child Interaction Therapy (I-PCIT) in Pediatric CancerRecruitingNCT06346782Not applicable1 country
- Basic and Applied Research on Extinction BurstsRecruitingNCT05925101Not applicable1 country
- Extensions of Resurgence as ChoiceRecruitingNCT05537610Not applicable1 country
- Empowering Youth With School Discipline Referrals as Peer CoachesRecruitingNCT07515742Not applicable1 country
- Behavioral Parent Training With and Without AI Support for Children With Disruptive BehaviorsRecruitingNCT07469215Not applicable1 country
- Tele-PCIT for Healthy Relationships in Families At-RiskRecruitingNCT07225010Not applicable1 country
- Step-by-Step: Evaluation of a Stepped Care ModelRecruitingNCT06902649Not applicable1 country
- Family STEPS: Family Check-Up+Not yet recruitingNCT07433361Not applicable1 country
- Personalizing Mental Health Treatment for Youth and FamiliesNot yet recruitingNCT07425366Not applicable
- Parental Technoference and Behavioral-Emotional Development in Early Childhood: A 6-Month Prospective StudyNot yet recruitingNCT073871331 country
- Problem Behavior Assessment and Intervention in IDEA Part C ServicesRecruitingNCT06771284Not applicable1 country
- Promoting Socioemotional Development in Early Childhood: Implementation and Evaluation of the VIPP-SD Parenting Intervention in PortugalRecruitingNCT07153198Not applicable1 country
- Referral Training and eGen TrialsRecruitingNCT06695663Not applicable1 country
- Behavioral Assessment and Treatment of Problem Behavior in Children With Cornelia de Lange SyndromeRecruitingNCT05829668Not applicable1 country
- Effects and Implementation of a Brief Version of Parent-Child Interaction TherapyNot yet recruitingNCT07201090Not applicable1 country
- Preventing Relapse of Problem Behavior Through Behavioral Economics: A Translational AnalysisRecruitingNCT06651606Not applicable1 country
- Stimulant Effects on Disruptive BehaviorRecruitingNCT03420339Phase 41 country
- Stop, Focus, Plan, and Change: Predicting Parent and Child Responses to a Brief, Telehealth Parent TrainingRecruitingNCT06505980Not applicable1 country
- Strong Mother Strong Special IndividualRecruitingNCT06535100Not applicable1 country
- Japi: Cognitive, Emotional and Social Stimulation for Preschool ChildrenRecruitingNCT06420544Not applicable1 country
- Brief Parent Training for Children With Behavioral Difficulties in Primary Care SettingsRecruitingNCT06160193Not applicable1 country
- Effectiveness of Child-Parent Relationship Therapy (CPRT)RecruitingNCT06087302Not applicable1 country
- Efficacy of Well-Being Promotion Program for Management of Emotional and Behavioural Problems Among AdolescentsRecruitingNCT06065579Not applicable1 country
- RUBIES in Educational SettingsRecruitingNCT05093686Not applicable1 country
- Relationship About Pregnancy Health and Offspring Developmental &Behavioral OutcomesRecruitingNCT040172861 country
- Digital Therapeutics for Behavior ProblemsActive, not recruitingNCT05647772Not applicable1 country
- Improving Student Mental Health Through a Universal Trauma-Informed InterventionActive, not recruitingNCT07842432Not applicable1 country
- A Mobile App to Improve 24-Hour Movement Guideline Adherence in PreschoolersActive, not recruitingNCT06667661Not applicable1 country