An observational study in Febrile Neutropenia and Fever, sponsored by M.D. Anderson Cancer Center. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2023-07-21.
Sponsored by M.D. Anderson Cancer Center · Observational
This trial uses an interview and a survey to gather information from cancer patients about the onset of their fever and the administration of antibiotics. Collecting information from patients may help doctors to assess the relationship between time to antibiotic administration and inhospital cause specific death, intensive care unit admission, hospital length of stay, and positive blood cultures.
PRIMARY OBJECTIVES:
I. To assess the prognostic value of the length of time between the time onset of fever and first antibiotic administration on cause specific 14 day mortality rate.
SECONDARY OBJECTIVES:
I. To assess the associations of the length of time between the time onset of fever and first antibiotic administration with intensive care unit (ICU) admission, ICU length of stay, length of hospitalization and percentage of patients with positive blood cultures.
OUTLINE:
Patients respond to a survey and participate in an interview with study staff about their fever and when they started feeling unwell.
155 studies on the registry are indexed under Febrile Neutropenia; 32 are open to participants now.
This study's enrollment of 315 is above the median of 132 across 57 observational studies indexed under Febrile Neutropenia.
Browse Febrile Neutropenia studies →M.D. Anderson Cancer Center is the lead sponsor of 3,044 studies on the registry; 578 are open to participants now.
Of its 608 completed or terminated interventional studies of FDA-regulated products, 407 (67%) have results posted.
Counted across the registry records on this site, refreshed daily.
Patients at the University of Texas MD Anderson Cancer Center
IInclusion criteria:
--> 18 years of age
Exclusion Criteria:
--Age \<18
Patients respond to a survey and participate in an interview with study staff about their fever and when they started feeling unwell.
Other: Interview · Other: Survey Administration
Take part in interview
Respond to survey
14 day cause specific mortality rate
Will perform univariate logistic regression analysis to assess the effect of time to antibiotic administration on death 14 days post fever onset. Will build multivariate logistic regression model(s) to further assess the effect of time to antibiotic administration on death 14 days post fever onset adjusting for other potential confounders.
Time frame: At 14 days
Cause specific death
Time frame: Up to 5 years
Intensive care unit (ICU) admission rate
Time frame: Up to 5 years
ICU length of stay
Linear regression model will be used to assess the multivariate relationship between time to antibiotic administration, patient demographic and clinical characteristics with ICU length of stay.
Time frame: Up to 5 years
Length of hospitalization
Linear regression model will be used to assess the multivariate relationship between time to antibiotic administration, patient demographic and clinical characteristics with length of hospitalization.
Time frame: Up to 5 years
Percentage of patients with positive blood cultures
Time frame: Up to 5 years
This study is completed, as verified in Jul 2023. You cannot join it, but the record below documents what was studied.
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