An interventional study of Zinc Sulfate and scaling and root planing in Chronic Periodontitis, sponsored by Cairo University. Status unknown. Per ClinicalTrials.gov, last updated 2019-04-23.
Sponsored by Cairo University · Not applicable, Interventional, and Treatment
To evaluate the effect of systemic administration of zinc on the gingival crevicular fluid level of total oxidant capacity in controlled Type-2 diabetic patients with stage-II and III periodontitis after non-surgical periodontal therapy.
Hypozincaemia and hyperzincuria is known to be present in patients with type-2 diabetes, and Zinc supplementation is known to be helpful in restoring plasma Zinc levels to normal,Zinc's deficiency can lead to an increase in circulating glucose due to beta cells malfunctioning and resistance to insulin, which makes it easier for type 2 diabetes mellitus (DM2) to happen ,Zinc was found to be a structural part of key anti-oxidant enzymes such as superoxide dismutase (SOD), and Zinc deficiency impaired their synthesis, leading to increased oxidative stress
1,635 studies on the registry are indexed under Periodontitis; 327 are open to participants now.
This study's planned enrollment of 34 is below the median of 45 across 1,191 interventional studies indexed under Periodontitis.
Browse Periodontitis studies →Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.
Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
systemic administration of Zinc cap of 50 mg elemental zinc as zinc sulphate, once a day for 12 weeks in addition to scaling and root planing
Drug: Zinc Sulfate
scaling and root planing
Procedure: scaling and root planing
systemic administration of Zinc sulfate with scaling and root planing
Also known as: Zinc Sulfate with scaling and root planing
scaling and root planing
change from baseline Hb-A1c
Time frame: change from baseline Hb-A1c at 3 monthes
Hb-A1c
Hb-A1c
Time frame: at the baseline and after 3 months
Probing pocket depth
Probing pocket depth Measured as the distance between the gingival margin and the apical part of the pocket will be measured using William's graduated periodontal probe.
Time frame: at the baseline and after 3 months
Clinical attachment level
It will be measured from the cemento-enamel junction till the apical part of the pocket.
Time frame: at the baseline and after 3 months
Gingival index
Gingival Index for a specific tooth == Average (points for the 4 surfaces)
Time frame: at the baseline and after 3 months
No study locations are listed for this record.
This study is status unknown, as verified in Apr 2019. You cannot join it, but the record below documents what was studied.
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Cairo University