An interventional study of Coronary flow and pressure measurement in patients with ventricular pacing in Coronary Microvascular Disease and Cardiac Pacemaker Syndrome, sponsored by University of Nebraska. Withdrawn. Open to participants aged 19 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-09-03.
Sponsored by University of Nebraska · Not applicable, Interventional, and Basic science
The study will examine role of transvenous pacing on coronary microcirculation.
To study the role of transvenous pacing on the coronary microcirculation. This will be accomplished by gathering data from invasive Fractional Flow Reserve (FFR) and Coronary Flow Reserve (CFR) with and without ventricular pacing.
123 studies on the registry are indexed under Microvascular Angina; 36 are open to participants now.
Browse Microvascular Angina studies →University of Nebraska is the lead sponsor of 473 studies on the registry; 66 are open to participants now.
Of its 75 completed or terminated interventional studies of FDA-regulated products, 46 (61%) have results posted.
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All patients 19 years of age or older with clinical evidence of coronary ischemia undergoing coronary angiogram, and who have a pacemaker.
Exclusion Criteria:
Patients with right ventricular pacing and evidence of coronary ischemia who have evidence of coronary ischemia who are to undergo coronary angiogram.When an intermediate stenosis (40-80%) has been identified angiographically, this lesion will undergo further hemodynamic assessment, All data including resting flow, FFR, CFR, vital signs, arrhythmias and patient symptoms will be recorded twice: once when the pacemaker is programmed to pace, and once when the PPM is reprogrammed such that the pacemaker is no longer pacing.
Diagnostic Test: Coronary flow and pressure measurement in patients with ventricular pacing
Patients with Biventricular pacing and evidence of coronary ischemia who have evidence of coronary ischemia who are to undergo coronary angiogram.When an intermediate stenosis (40-80%) has been identified angiographically, this lesion will undergo further hemodynamic assessment, All data including resting flow, FFR, CFR, vital signs, arrhythmias and patient symptoms will be recorded twice: once when the pacemaker is programmed to pace, and once when the PPM is reprogrammed such that the pacemaker is no longer pacing.
Diagnostic Test: Coronary flow and pressure measurement in patients with ventricular pacing
Coronary flow and pressure measurement in patients with ventricular pacing
Patients that exhibit coronary microvascular resistance and dysfunction as reflected by FFR
Microvascular dysfunction with pacing
Time frame: Up to 12 months
Patients that exhibit coronary microvascular resistance and dysfunction as reflected by CFR
Microvascular dysfunction with pacing
Time frame: Up to 12 months
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
This study is withdrawn, as verified in Aug 2024. You cannot join it, but the record below documents what was studied.
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