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CompletedNCT03884738Updated Apr 22, 2020

Strengthening Effect on Hamstring's Passive Mechanical Properties

An interventional study of Concentric Exercise and Nordic Eccentric exercise in Sports Physical Therapy, sponsored by Hacettepe University. Completed at 1 site in Turkey. Open to male participants aged 18 Years to 30 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-04-22.

Sponsored by Hacettepe University · Not applicable, Interventional, and Basic science

Phase
Not applicable
Study type
Interventional
Enrollment
42
Allocation
Randomized
Ages
18 Years to 30 Years
Sex
Male
01

Study summary

The purpose of this study was to investigate effects of different strengthening methods on hamstring muscle group's passive mechanical properties and to investigate this effect's relation with performance changes in healthy individuals. 42 healthy sedentary male participated in this study. Passive mechanical properties and strength of hamstring and quadriceps muscles, flexibility of hamstring muscles, anaerobic explosive strength, reaction time, agility were measured. Participants randomized evenly into one of three groups; eccentric, concentric and neuromuscular electrical stimulation (NMES). After 8 weeks training period, participants were measured again.

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Conditions studied

  • Sports Physical Therapy

Keywords

  • Muscle Tonus
  • Elasticity
  • Electric Stimulation Therapy
  • Physical Conditioning, Human
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In context

Lead sponsor

Hacettepe University is the lead sponsor of 983 studies on the registry; 212 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 30 Years
Sexes eligible
Male
Accepts healthy volunteers
Yes

Inclusion criteria

  • being sedentary

Exclusion criteria

Exclusion Criteria:

  • Having knee, hip and/or back pain
  • Having a cardiovascular condition/disease
  • History of previous knee and/or hip surgery
  • Having a diagnose of any systemic disease
  • History of previous hamstring injury
  • Being physically active within last year ( Regular activity at least 3 days a week and continuity of at least 2 months was accepted as being physically active)
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Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
42 participants (actual)

Study arms

  • Active comparator
    Concentric

    Leg Curl Training

    Other: Concentric Exercise

  • Active comparator
    Eccentric

    Nordic Hamstring Training

    Other: Nordic Eccentric exercise

  • Active comparator
    Neuromuscular Electrical Stimulation

    Stimulation Training

    Other: Neuromuscular Electrical Stimulation

Interventions

  • OtherConcentric Exercise

    Leg Curl Machine: 1st week - 1st day is 10 maximum repeat test. 2nd week - 2 days of training - 2 sets of 6 repeats. %60 percent of maximum load. 3rd week - 3 days of training - 3 sets of 6-8 repeats. %60-80 of maximum load. 4th-8th week - 3 days of training - 3 sets of 8-12 repeats. when 3 sets of 12 achieved, load was increased with 2.5kg.

  • OtherNordic Eccentric exercise

    1. st week - 1 day - 2 sets of 5 repeats. 2. nd week - 2 days - 2 sets of 6 repeats. 3. rd week - 3 days - 3 sets of 6-8 repeats. 4. th week - 3 days - 3 sets of 8-10 repeats. 5-8th weeks - 3 days - 3 sets of 12-8 repeats. When achieved 3 sets of 12 repeats with full range, speed was increased.

  • OtherNeuromuscular Electrical Stimulation

    8 weeks, three times per week, 15 minutes of bilateral hamstring stimulation. 100 Hz. frequency, 600 microsecond duration rectangular current

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What researchers measure

Primary outcomes

  1. Passive Mechanical Properties

    Tone, Elasticity and Stiffness evaluation. Evaluated with Myotonometer-3

    Time frame: Change from baseline passive mechanical properties at 8 weeks

Secondary outcomes

  1. Flexibility Measurement

    Sit and reach test was used for hamstring flexibility

    Time frame: Change from baseline flexibility at 8 weeks

  2. Muscle Strength Measurement

    Hamstring and Quadriceps strength were measured with LaFayette Manuel Muscle Tester

    Time frame: Change from baseline muscle strength at 8 weeks

  3. Agility Measurement

    Illinois Agility Test was used for agility measurement

    Time frame: Change from baseline agility time at 8 weeks

  4. Anaerobic Explosive Power

    Jump and Reach test was administered

    Time frame: Change from baseline anaerobic explosive power at 8 weeks

  5. Reaction Time

    ruler drop test was used for reaction timing

    Time frame: Change from baseline reaction time at 8 weeks

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Study locations

1 site
  • Hacettepe University
    Ankara, 06100, Turkey
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References and documents

Publications

  • Ayala F, Sainz de Baranda P, De Ste Croix M, Santonja F. Reproducibility and criterion-related validity of the sit and reach test and toe touch test for estimating hamstring flexibility in recreationally active young adults. Phys Ther Sport. 2012 Nov;13(4):219-26. doi: 10.1016/j.ptsp.2011.11.001. Epub 2012 Jan 23. PubMed 23068896 ↗
  • Mentiplay BF, Perraton LG, Bower KJ, Adair B, Pua YH, Williams GP, McGaw R, Clark RA. Assessment of Lower Limb Muscle Strength and Power Using Hand-Held and Fixed Dynamometry: A Reliability and Validity Study. PLoS One. 2015 Oct 28;10(10):e0140822. doi: 10.1371/journal.pone.0140822. eCollection 2015. PubMed 26509265 ↗
  • Amiri-Khorasani M, Sahebozamani M, Tabrizi KG, Yusof AB. Acute effect of different stretching methods on Illinois agility test in soccer players. J Strength Cond Res. 2010 Oct;24(10):2698-704. doi: 10.1519/JSC.0b013e3181bf049c. PubMed 20168255 ↗
  • Schwesig R, Koke A, Fischer D, Fieseler G, Jungermann P, Delank KS, Hermassi S. Validity and Reliability of the New Handball-Specific Complex Test. J Strength Cond Res. 2016 Feb;30(2):476-86. doi: 10.1519/JSC.0000000000001061. PubMed 26815176 ↗
  • Mjolsnes R, Arnason A, Osthagen T, Raastad T, Bahr R. A 10-week randomized trial comparing eccentric vs. concentric hamstring strength training in well-trained soccer players. Scand J Med Sci Sports. 2004 Oct;14(5):311-7. doi: 10.1046/j.1600-0838.2003.367.x. PubMed 15387805 ↗
  • Glaviano NR, Langston WT, Hart JM, Saliba S. Influence of patterned electrical neuromuscular stimulation on quadriceps activation in individuals with knee joint injury. Int J Sports Phys Ther. 2014 Dec;9(7):915-23. PubMed 25540707 ↗

Individual participant data

Plan to share: No

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 22, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03884738
Lead sponsor
Hacettepe University
Responsible party
Özgün Uysal (Research Assistant, Hacettepe University) — Principal investigator
First posted
Mar 21, 2019
Start date
Mar 21, 2019
Primary completion
Dec 1, 2019
Completion
Dec 1, 2019
Last update
Apr 22, 2020

Study contacts

tuzun fırat, Assoc. Prof.
study director · Hacettepe University

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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