CClinicalTrials.gg
Status unknownNCT03816124Updated Jan 25, 2019

The Effect of Radiofrequency Ablation of Genicular Nerves on Postural Stability in Patients With Knee Osteoarthritis

An interventional study of radiofrequency ablation in Osteoarthritis, Knee, sponsored by Marmara University. Status unknown at 1 site in Turkey. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-01-25.

Sponsored by Marmara University · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Jan 2019), so the status shown — last known as Recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Not applicable
Ages
18 Years to 65 Years
Sex
All
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Study summary

In advanced knee osteoarthritis, postural stability is also disturbed. There are some concerns about performing radiofrequency ablation to genicular nerves since this may further decrease the postural stability of the patient. The aim of this study is to see if application of genicular radiofrequency causes a significant change in postural stability.

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Conditions studied

  • Osteoarthritis, Knee

Keywords

  • osteoarthritis
  • radiofrequency ablation
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In context

Osteoarthritis

4,398 studies on the registry are indexed under Osteoarthritis; 582 are open to participants now.

This study's planned enrollment of 30 is below the median of 70 across 3,440 interventional studies indexed under Osteoarthritis.

Browse Osteoarthritis studies →

Lead sponsor

Marmara University is the lead sponsor of 576 studies on the registry; 136 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Stage 3 and 4 knee osteoarthritis according to Kellgren-Lawrance scale
  • Knee pain more than 3 months

Exclusion criteria

Exclusion Criteria:

  • Neurological diseases such as polyneuropathies
  • Presence of severe psychiatric disorders
  • Hemodynamic instability
  • History of any surgery from the knee
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Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
30 participants (estimated)

Study arms

  • Experimental
    Genicular RF

    Patients who will receive genicular radiofrequency ablation

    Procedure: radiofrequency ablation

Interventions

  • Procedureradiofrequency ablation

    radiofrequency ablation of the genicular nerves

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What researchers measure

Primary outcomes

  1. Visual analogue scale

    The change of pain will be evaluated with 10 cm visual analogue scale will be applied to the patients, 0 being no pain while 10 being intolerable pain

    Time frame: 3 weeks and 3 months after the intervention

Secondary outcomes

  1. Postural stability

    The change of weight bearing indexes of both feet will be measured

    Time frame: 3 weeks and 3 months after the treatment

  2. WOMAC

    Western Ontario \& McMaster Universities Osteoarthritis Index

    Time frame: 3 weeks and 3 months after the treatment

07

Study locations

1 of 1 sites recruiting
  • Marmara University School of Medicine Department of Physical Medicine and Rehabilitation
    Istanbul, 34899, Turkey
    Recruiting
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 25, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03816124
Lead sponsor
Marmara University
Responsible party
Sponsor
First posted
Jan 25, 2019
Start date
Dec 1, 2018
Primary completion
Jun 2019 (estimated)
Completion
Dec 2019 (estimated)
Last update
Jan 25, 2019

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jan 2019. You cannot join it, but the record below documents what was studied.

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