An interventional study of lymph node dissection in Lymph Node Metastases, sponsored by Zhejiang University. Not yet recruiting. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2019-07-05.
Sponsored by Zhejiang University · Not applicable, Interventional, and Treatment
This study is divided into three stages. In the first stage, the investigators try to explore the objective clinical imaging standard of cN0PTC on the basis of previous studies, formulate the "clinical imaging standard of cN0PTC", and randomly enroll 2000 patients under the premise of meeting the standard to establish the "predictive model of cN0-pN+PTC".
In the second stage, 2000 patients will be enrolled to test and improve the evaluation efficiency of "cN0-pN+PTC prediction model".
In the third stage, 2 000 patients without lymph node metastasis assessed by "cNo-pN+ PTC prediction model" will be randomly divided into experimental group and control group. The experimental group will be treated with pCND, while the experimental group will be treated without pCND. The central lymph node metastasis probability, the number and size of metastatic lymph nodes in the control group will be observed after operation. The two groups will be followed up for 5, 10, 15 and 20 years to observe the RFS and OS, so as to further evaluate the "cN0-pN+PTC prediction model" scientifically.
244 studies on the registry are indexed under Lymphatic Metastasis; 91 are open to participants now.
This study's planned enrollment of 6,000 is above the median of 90 across 127 interventional studies indexed under Lymphatic Metastasis.
Browse Lymphatic Metastasis studies →Zhejiang University is the lead sponsor of 351 studies on the registry; 165 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Phase I and II:
Phase III:
Exclusion Criteria:
Procedure: lymph node dissection
Procedure: lymph node dissection
The patient was operated under general anesthesia with cervical hyper extension. The affected side or bilateral glandular lobes were resected routinely, which was confirmed as PTC by frozen section. Then one or both central lymph node dissection were separately packed and sent for examination. Scope of lymph node dissection in central carotid region: hyoid bone at the upper border, anonymous artery at the lower border, bilateral common carotid artery at the inner edge, shallow from the superficial layer of deep cervical fascia, deep to the deep layer of deep cervical fascia (anterior fascia). The right recurrent laryngeal nerve (RLN) passes through the central area of the right neck and should be specially protected.
Recurrence of thyroid cancer
Time frame: Participants will be followed from the operation to 20 year (maximum)
No study locations are listed for this record.
This study is not yet recruiting, as verified in Jul 2019. You cannot join it, but the record below documents what was studied.
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Zhejiang University