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CompletedNCT03807635Updated Jan 22, 2019

Simulated Clinical Use Testing on Safety Lancets (Test A)

An interventional study of ergoLance safety lancet and Acti-Lance safety lancet in Needle Stick, sponsored by HTL-Strefa S.A.. Completed at 2 sites in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-01-22.

Sponsored by HTL-Strefa S.A. · Not applicable, Interventional, and Other

Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Non-randomized
Ages
18 Years and older
Sex
All
01

Study summary

A simulated clinical use testing on the HTL-Strefa's safety lancets

Read the detailed description

This study aims to evaluate the safety of the use of the safety lancets: ergoLance and Acti-Lance in the prevention of NSI and to evaluate the user's opinion with regards to the handling characteristics of the medical devices.

The simulated use clinical study will involve healthcare professionals (HCPs) who routinely use safety lancets to collect blood samples and lay persons.

02

Conditions studied

  • Needle Stick

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Keywords

  • needlestick
  • needlestick injury
  • safety lancet
  • sharps injury prevention
  • capillary blood sampling
03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

The inclusion criteria for HCP and lay person evaluators have been chosen based on FDA guidance:

  • (HCP evaluators only) - evaluators who routinely use safety lancets to collect capillary blood samples (prevention of the learning curve artifacts)
  • evaluators will be United States (US) residents
  • evaluators can read, write, and speak English
  • evaluators are at least 18 years old
  • evaluators are able to understand and provide signed consent for the study
  • evaluators are willing to comply with the study protocol, including being willing to answer questions and complete questionnaires.
  • evaluators have no concerns about the ability to perform the simulated skin pricking.

Lay person evaluators will have a diverse range of ages (18+ years), socioeconomic statuses, and race/ethnic backgrounds. UL-Wiklund will recruit some lay person evaluators with reduced vision and dexterity. Users without safety lancet experience may also be included in this simulated clinical use study.

Exclusion criteria

Exclusion Criteria:

HCPs:

  • They do not routinely use safety lancets to collect capillary blood samples,
  • They cannot read, write, and speak English,
  • They or a family member have a business or consulting relationship with a pharmaceutical or medical device company, or
  • They have participated in a product evaluation or marketing study involving safety lancets within the last six months

Lay people:

  • They cannot read, write, and speak English,
  • They or a family member have a business or consulting relationship with a pharmaceutical or medical device company, or
  • They have participated in a product evaluation or marketing study involving safety lancets within the last six months
04

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
20 participants (actual)

Study arms

  • Experimental
    simulation of skin pricking type 450

    The evaluator simulated the capillary blood sampling with the safety lancet type 450

    Device: ergoLance safety lancet

  • Experimental
    simulation of skin pricking type 610

    The evaluator simulated the capillary blood sampling with the safety lancet type 610

    Device: Acti-Lance safety lancet

Interventions

  • DeviceergoLance safety lancet

    The ergoLance contact activated safety lancets type 450 are sterile, single-use safety lancets designed for the sampling of capillary blood from the fingertip of patients.

  • DeviceActi-Lance safety lancet

    The Acti-Lance safety lancet type 610 is a sterile, single use device used to carry out skin punctures for the purpose of collecting capillary blood samples.

05

What researchers measure

Primary outcomes

  1. The true failure rate of the tested devices

    Time frame: At time of testing, up to 90 minutes

  2. Effectiveness of the safety lancet's sharps injury prevention features

    Evaluator questionnaire using five-point response Likert scale (coded from 1 "strongly disagree" to 5 "strongly agree") to measure respondents' attitudes to a particular question or statement. Numbers assigned to Likert scale express a "greater than" relationship.

    Time frame: At time of testing, up to 90 minutes

Secondary outcomes

  1. Subjective assessments regarding evaluators' interactions with the tested safety lancets

    Evaluator questionnaire using five-point response Likert scale (coded from 1 "strongly disagree" to 5 "strongly agree") to measure respondents' attitudes to a particular question or statement. Numbers assigned to Likert scale express a "greater than" relationship.

    Time frame: At time of testing, up to 90 minutes

  2. Safety of the devices based on the evaluators' assessments (five-point response scale)

    Evaluator questionnaire using five-point response Likert scale (coded from 1 "strongly disagree" to 5 "strongly agree") to measure any and all observed needlestick injuries and device malfunctions. Numbers assigned to Likert scale express a "greater than" relationship.

    Time frame: At time of testing, up to 90 minutes

  3. Various aspects of the ease of use.

    Evaluator questionnaire using five-point response Likert scale (coded from 1 "strongly disagree" to 5 "strongly agree") to measure respondents' attitudes to a particular question or statement. Numbers assigned to Likert scale express a "greater than" relationship.

    Time frame: At time of testing, up to 90 minutes

  4. Any handling, usability questions / issues associated with the device

    Evaluator questionnaire using five-point response Likert scale (coded from 1 "strongly disagree" to 5 "strongly agree") to measure respondents' attitudes to a particular question or statement. Numbers assigned to Likert scale express a "greater than" relationship.

    Time frame: At time of testing, up to 90 minutes

06

Study locations

2 sites
  • UL LLC
    Chicago, Illinois 60606, United States
  • Schlesinger Associates
    Boston, Massachusetts 02116, United States
07

Registry details

Key details

Study ID
NCT03807635
Lead sponsor
HTL-Strefa S.A.
Responsible party
Sponsor
First posted
Jan 17, 2019
Start date
Nov 30, 2018
Primary completion
Dec 13, 2018
Completion
Dec 13, 2018
Last update
Jan 22, 2019

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
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