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WithdrawnNCT03781141Updated Mar 5, 2026

Wound Closure Study in Carpal Tunnel and Trigger Finger Surgery

An interventional study of Wound closure in Carpal Tunnel Syndrome and Trigger Finger, sponsored by Mayo Clinic. Withdrawn at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-03-05.

Sponsored by Mayo Clinic · Not applicable, Interventional, and Treatment

Why this study was withdrawn
change in practice pattern
Phase
Not applicable
Study type
Interventional
Enrollment
0
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

Does a difference in patient satisfaction and cosmetic outcome exist between wound closure with absorbable or non-absorbable sutures.

Read the detailed description

The study will involve randomizing patients to wound closure with absorbable or non-absorbable sutures. We will if scar formation (symptoms and aesthetics) if different between the two types of closures as determined by the patient and observer scar assessment scale version 2.0 (POSAS) and the patient-rated wrist/hand evaluation (PRWHE), between absorbable and non-absorbable suture for wound closure of open carpal tunnel release and trigger finger pulley release.

02

Conditions studied

  • Carpal Tunnel Syndrome
  • Trigger Finger
03

In context

Carpal Tunnel Syndrome

587 studies on the registry are indexed under Carpal Tunnel Syndrome; 134 are open to participants now.

Browse Carpal Tunnel Syndrome studies →

Lead sponsor

Mayo Clinic is the lead sponsor of 3,269 studies on the registry; 672 are open to participants now.

Of its 452 completed or terminated interventional studies of FDA-regulated products, 321 (71%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Any patient greater than or equal to 18 years of age.
  • Any patient undergoing primary open carpal tunnel release or primary trigger finger pulley release

Exclusion criteria

Exclusion Criteria:

  • Any patient identified outside of the proposed study time period.
  • Any patient receiving revision surgery
  • Patients who have had prior ipsilateral palmar or finger surgery
  • Patients with Dupuytren's disease
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Single group
Masking
Single (Outcomes assessor)
Enrollment
0 participants (actual)

Study arms

  • Experimental
    Absorbable suture

    Wound closure with absorbable suture.

    Procedure: Wound closure

  • Active comparator
    Non-absorbable suture

    Wound closure with non-absorbable suture.

    Procedure: Wound closure

Interventions

  • ProcedureWound closure

    Comparison of two wound closures

06

What researchers measure

Primary outcomes

  1. Scar formation with the Patient and Observer Scare Assessment Scale

    Blinded scar assessment utilizing the patient and observer scar assessment scale version 2.0 (POSAS). The POSAS is scored from the perspective of the patient and a blinded observer independently. Scores range from 1 to 10 with 1 indicating normal skin and 10 indicating the worst scar imaginable. The 1 to 10 scoring is performed in 6 domains of various scar characteristics to obtain a total score ranging from 10 to 60. Additionally, there is an overall scar appearance score that ranges from 1 to 10 with 1 indicating normal skin and 10 indicating the worst scar imaginable.

    Time frame: 1 year

07

Study locations

1 site
  • Mayo Clinic in Rochester
    Rochester, Minnesota 55905, United States
08

References and documents

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 5, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03781141
Lead sponsor
Mayo Clinic
Responsible party
Peter C. Rhee (Principal Investigator, Mayo Clinic) — Principal investigator
First posted
Dec 19, 2018
Start date
Dec 1, 2019
Primary completion
Mar 1, 2026
Completion
Mar 1, 2026
Last update
Mar 5, 2026

Study contacts

Peter C Rhee
principal investigator · Mayo Clinic

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is withdrawn, as verified in Mar 2026. You cannot join it, but the record below documents what was studied.

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