An interventional study of Neo dental implant Alpha Bio Tec. Ltd. in Dental Implants,Peri-implantitis,Smoking, sponsored by Rambam Health Care Campus. Completed at 1 site in Israel. Open to participants aged 20 Years to 85 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-08-17.
Sponsored by Rambam Health Care Campus · Not applicable, Interventional, and Diagnostic
The Aim of this study randomized prospective clinical trial is to examine and compare periimplant tissue changes between heavy smokers and non-smokers at 12 months post loading using the alpha Bio Neo standard diameter implants with conical abutment.
Peri-implant marginal bone level is one of the most important references criteria to monitor peri-implant health.A radiographically measured marginal bone loss of up to 1.5 mm during the first year of loading, followed by a marginal bone loss of up to 0.2 mm for each succeeding year, is an acceptable criterion to determine implant success.
Smoking has been implicated in many adverse systemic outcomes, including tooth loss, alveolar bone loss and dental implant failure.
Platform switching, also known as platform shifting, is whenever an abutment is used that is smaller in diameter than the implant platform. Platform switching can help prevent crestal bone loss.
The hypothesis of the present study is that the use of conical abutment might reduce marginal bone loss around dental implants in both smokers and non-smokers alike.
268 studies on the registry are indexed under Smoking; 136 are open to participants now.
This study's enrollment of 32 is below the median of 120 across 211 interventional studies indexed under Smoking.
Browse Smoking studies →Rambam Health Care Campus is the lead sponsor of 456 studies on the registry; 33 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Marginal bone changes after 1 year after implant installation using Neo dental implant Alpha Bio Tec. Ltd.
Device: Neo dental implant Alpha Bio Tec. Ltd.
Marginal bone changes after 1 year after implant installation using Neo dental implant Alpha Bio Tec. Ltd.
Device: Neo dental implant Alpha Bio Tec. Ltd.
Neo dental implant is used to restore missing teeth
marginal bone loss
Standardized periapical radiographs will be used to assess changes in radiographic bone height.
Time frame: 6 months and 18 months after implantation.
Implants probing depth (IPD)
will be measured by inserting a probe to the gingival pocket at six sites around implant
Time frame: 4 months, 6 months and 16 months after implantation
Bleeding on probing
will be measured by inserting a probe to the gingival pocket at six sites around each implant: Dichotomic measurments: Yes/No
Time frame: 4 months, 6 months and 16 months after implantation
Labial gingival recession
will be measured using the incisal edge. occlusal plan as a fixed reference point.
Time frame: 4 months, 6 months and 16 months after implantation
Implant stability
Osstel measurements
Time frame: Immediatly after implant installation (day 0) and 4 months after implantation
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Aug 2025. You cannot join it, but the record below documents what was studied.
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Rambam Health Care Campus