An interventional study of Phacoemulsification with and without Trypan Blue capsule staining in Cataract Diabetic, sponsored by Assiut University. Completed at 1 site in Egypt. Open to participants aged 25 Years to 70 Years. Per ClinicalTrials.gov, last updated 2018-11-28.
Sponsored by Assiut University · Not applicable, Interventional, and Treatment
This study examines the use of Trypan Blue staining of the corneal endothelium in patients undergoing phacoemulsification. It is a single-center prospective, randomized individual cohort study. One eye in each patient with diabetic retinopathy will undergo phacoemulsification without Trypan Blue capsule staining (control eye) while the other eye will undergo phacoemulsification with Trypan Blue capsule staining (study eye). Both eyes will undergo intraocular lens implantation. Preoperative and four-week postoperative quantitative and qualitative morphometric endothelial cell analyses of the cornea will be performed using noncontact specular microscopy.
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This study's enrollment of 65 is below the median of 80 across 1,155 interventional studies indexed under Cataract.
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Phacoemulsification with Trypan Blue capsule staining of the anterior lens capsule in patients with diabetic retinopathy
Procedure: Phacoemulsification with and without Trypan Blue capsule staining
Phacoemulsification without Trypan Blue capsule staining of the anterior lens capsule in patients with
Procedure: Phacoemulsification with and without Trypan Blue capsule staining
Phacoemulsification for patients with diabetic retinopathy having cataract in both eyes. One eye underwent phacoemulsification with trypan blue capsule staining and the other eye underwent phacoemulsification without trypan blue.
Endothelial cell density
Time frame: 4 weeks
Endothelial cell coefficient of variation
Time frame: 4 weeks
Percent of hexagonal cells
Time frame: 4 weeks
Mean corneal thickness
Time frame: 4 weeks
Plan to share: No
This study is completed, as verified in Nov 2018. You cannot join it, but the record below documents what was studied.
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Assiut University