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Not yet recruitingNCT06192134Updated Nov 4, 2026

Continuous Passive Motion Device for Children With Arthrogryposis

An interventional study of CPM device in Arthrogryposis, sponsored by Nemours Children's Clinic. Not yet recruiting. Open to participants aged 3 Years to 7 Years. Per ClinicalTrials.gov, last updated 2026-11-04.

Sponsored by Nemours Children's Clinic · Not applicable, Interventional, and Prevention

Updated Nov 4, 2026Start date movedPrimary completion moved+1 moreGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
5
Allocation
Not applicable
Ages
3 Years to 7 Years
Sex
All
01

Study summary

The Investigators are investigating a continuous passive motion device to exercise the knee of young children with arthrogryposis after they have had knee surgery.

Read the detailed description

The investigators will measure the effect of continuous passive motion (CPM) of the knee joint post-surgery on young children with arthrogryposis. The investigators have developed a motorized brace that will move the joint through a prescribed range of motion and speed while the subject is seated. The objective of this pilot study is to develop the device from subject feedback and determine the right dose and speed of CPM to provide. CPM is routinely used for adults and older children after surgery to maintain range of motion. The machines used are too large for young children therefore the investigators have developed a prototype for small sized kids that will exercise their knee joint post-surgery.

02

Conditions studied

  • Arthrogryposis

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03

In context

Arthrogryposis

16 studies on the registry are indexed under Arthrogryposis; 5 are open to participants now.

Browse Arthrogryposis studies →

Lead sponsor

Nemours Children's Clinic is the lead sponsor of 130 studies on the registry; 26 are open to participants now.

Of its 9 completed or terminated interventional studies of FDA-regulated products, 6 (67%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
3 Years to 7 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Children with arthrogryposis
  • Children between 3 and 7 years of age
  • Children who have had recent knee surgery

Exclusion criteria

Exclusion Criteria:

  • Children older than 7
  • Children unable to cooperate with protocol steps
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
5 participants (estimated)

Study arms

  • Experimental
    CPM group

    group receiving CPM therapy

    Device: CPM device

Interventions

  • DeviceCPM device

    CPM brace

06

What researchers measure

Primary outcomes

  1. range of motion

    knee range of motion

    Time frame: 2 weeks

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedDate before it movedWhere the date was before it moved

Start is estimated for Jun 2027; primary completion for May 2029, 23 months later.

Since we started tracking on Sep 25, 2026, the dates moved once, on Nov 4, 2026: start Dec 2026 → Jun 2027, primary completion May 2028 → May 2029 and completion Jun 2028 → Jun 2029.

Earlier changes are on the record history on ClinicalTrials.gov ↗

How these figures are worked out, and which studies are left out of them.

Registered
Dec 20, 2023
First posted
Jan 5, 2024
StartEst.
Jun 2027was Dec 2026
Primary completionEst.
May 2029was May 2028
CompletionEst.
Jun 2029was Jun 2028
Last update
Nov 4, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Start date
Dec 2026→Jun 2027
Nov 4, 2026
Primary completion
May 2028→May 2029
Nov 4, 2026
Study completion
Jun 2028→Jun 2029
Nov 4, 2026
Show all 1 update
  1. Nov 4, 2026
    Start date Dec 2026→Jun 2027
    Primary completion May 2028→May 2029
    Study completion Jun 2028→Jun 2029
    + 1 other change: verification date

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT06192134
Responsible party
Tariq Rahman (Principal Research Engineer, Nemours Children's Clinic) — Principal investigator
First posted
Jan 5, 2024
Start date
Jun 2027 (estimated)
Primary completion
May 2029 (estimated)
Completion
Jun 2029 (estimated)
Last update
Nov 4, 2026

Study contacts

Tariq Rahman
Contact
trahman@nemours.org
302 651 6831

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Nov 2026. You cannot join it, but the record below documents what was studied.

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