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CompletedNCT03613818Updated Apr 1, 2021Results posted

Efficacy of a Web-Based Alcohol Intervention for High School Students

An interventional study of eCHECKUP TO GO in Underage Drinking, sponsored by Boise State University. Completed at 1 site in United States. Open to participants aged 16 Years to 18 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-04-01.

Sponsored by Boise State University · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
311
Allocation
Randomized
Ages
16 Years to 18 Years
Sex
All
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Study summary

This study evaluates the efficacy of the eCHECKUP TO GO as an intervention to reduce underage drinking and the associated negative consequences among high school seniors. The aim of this project is to provide a brief, low cost intervention that can be easily disseminated as a school-based intervention to address this important public health problem.

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Conditions studied

  • Underage Drinking

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03

In context

Underage Drinking

44 studies on the registry are indexed under Underage Drinking; 13 are open to participants now.

This study's enrollment of 311 is below the median of 360 across 43 interventional studies indexed under Underage Drinking.

Browse Underage Drinking studies →

Lead sponsor

Boise State University is the lead sponsor of 11 studies on the registry; 3 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
16 Years to 18 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Senior enrolled in high school sites

Exclusion criteria

Exclusion Criteria:

  • none
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Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
311 participants (actual)

Study arms

  • Experimental
    eCHECKUP TO GO

    Brief, web-based alcohol intervention

    Behavioral: eCHECKUP TO GO

  • No intervention
    Control

    Assessment only

Interventions

  • BehavioraleCHECKUP TO GO

    eCHECKUP TO GO is a personalized normative feedback intervention intended to help participants make better choices about alcohol use by changing beliefs about alcohol, alcohol expectancies, and perceptions of peer drinking

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What researchers measure

Primary outcomes

  1. Weekly Drinking

    Daily Drinking Questionnaire Weekly drinking was assessed with the question "Given that it is a typical week, please write the number of drinks you probably would have each day." A response scale is provided for each day of the week (e.g., Monday__, Tuesday__, etc.)." Weekly drinking was calculated by combining the reports for the seven days of the week (sum of the 7 days). Minimum = 0; Maximum = none Sample score range: Minimum = 0; Maximum = 26 Higher scores are worse outcomes

    Time frame: Baseline, 1 month follow-up, and 6-month follow up

  2. Peak Drinking Quantity

    Quantity ⁄Frequency ⁄Peak Questionnaire Peak drinking quantity was assessed with the question "What is the most number of drinks that you have consumed on any given night in the past month?" Minimum = 0; Maximum = none Sample score range: Minimum = 0; Maximum = 25 Higher scores are worse outcomes

    Time frame: Baseline, 1 month follow-up, and 6-month follow up

  3. Frequency of Alcohol Use

    Quantity ⁄Frequency ⁄Peak Questionnaire Frequency of alcohol use was assessed with the question "How often do you use alcohol?" with responses provided on an 8-point Likert scale with options ranging from "0" to "7" ("Do not drink alcohol" to "Every day"). Items were reverse scores so higher scores represent higher levels of drinking frequency. Minimum = 0; Maximum = 7 Sample score range: Minimum = 0; Maximum = 7 Higher scores are worse outcomes

    Time frame: Baseline, 1 month follow-up, and 6-month follow up

  4. Blood Alcohol Concentration

    Blood alcohol concentration was calculated using the Widmark Formula (1932/1981); BAC = \[Alcohol consumed in grams / (Body weight in grams x r)\] x 100. In this formula, "r" is the gender constant. Minimum = 0; Maximum = none Sample score range: Minimum = 0; Maximum = .62 Higher scores are worse outcomes

    Time frame: Baseline, 1 month follow-up, and 6-month follow up

  5. Heavy Episodic Drinking

    Heavy Episodic Drinking is defined as having 5 or more drinks in a row for males and 3 or more for females in a 2 hour period in the past month. The number of drinks was based on research by Donovan (2009) establishing cut-points for children and adolescents. Participants were asked: "Males: Think back over the last two weeks. How many times have you had 5 or more drinks in a two hour period?" "Females: Think back over the last two weeks. How many times have you had 3 or more drinks in a two hour period?" Minimum = 0; Maximum = none Sample score range: Minimum = 0; Maximum = .76 Higher scores are worse outcomes

    Time frame: Baseline, 1 month follow-up, and 6-month follow up

Secondary outcomes

  1. Alcohol-Related Consequences

    Rutgers Alcohol Problems Inventory Alcohol-related consequences were measured using the Rutgers Alcohol Problems Inventory. The Rutgers Alcohol Problems Inventory is a 23-item scale. Participants were asked "How many times have the following scenarios happened to you while you were consuming alcohol or as a result of your drinking in the past 30 days." Responses were measured on a 5-point scale ranging from 0 (never) to 4 (more than 10 times). A total consequence score is created by summing the 23 items. Minimum = 0; Maximum = 92 Sample score range: Minimum = 0; Maximum = 24 Higher scores are worse outcomes

    Time frame: Baseline and 6-month follow up

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Results

Posted Apr 1, 2021

Participant flow

Participant flow — Overall Study
MilestoneeCHECKUP TO GOControl
Started174137
Completed137110
Not completed3727

Outcome measures

PrimaryWeekly Drinking

Daily Drinking Questionnaire Weekly drinking was assessed with the question "Given that it is a typical week, please write the number of drinks you probably would have each day." A response scale is provided for each day of the week (e.g., Monday__, Tuesday__, etc.)." Weekly drinking was calculated by combining the reports for the seven days of the week (sum of the 7 days). Minimum = 0; Maximum = none Sample score range: Minimum = 0; Maximum = 26 Higher scores are worse outcomes

Time frame:
Baseline, 1 month follow-up, and 6-month follow up
Reported as:
Mean · drinks per week
Weekly Drinking
drinks per weekeCHECKUP TO GOControl
Basline4.14 ± 6.743.06 ± 6.39
1 Month Follow-Up2.92 ± 4.932.55 ± 5.32
6 Month Follow-Up2.23 ± 3.942.14 ± 5.04
PrimaryPeak Drinking Quantity

Quantity ⁄Frequency ⁄Peak Questionnaire Peak drinking quantity was assessed with the question "What is the most number of drinks that you have consumed on any given night in the past month?" Minimum = 0; Maximum = none Sample score range: Minimum = 0; Maximum = 25 Higher scores are worse outcomes

Time frame:
Baseline, 1 month follow-up, and 6-month follow up
Reported as:
Mean · drinks
Peak Drinking Quantity
drinkseCHECKUP TO GOControl
Baseline5.10 ± 6.012.81 ± 5.13
1 Month Follow-Up3.65 ± 4.482.53 ± 4.89
6 Month Follow-Up3.63 ± 4.862.40 ± 4.58
PrimaryFrequency of Alcohol Use

Quantity ⁄Frequency ⁄Peak Questionnaire Frequency of alcohol use was assessed with the question "How often do you use alcohol?" with responses provided on an 8-point Likert scale with options ranging from "0" to "7" ("Do not drink alcohol" to "Every day"). Items were reverse scores so higher scores represent higher levels of drinking frequency. Minimum = 0; Maximum = 7 Sample score range: Minimum = 0; Maximum = 7 Higher scores are worse outcomes

Time frame:
Baseline, 1 month follow-up, and 6-month follow up
Reported as:
Mean · score on a scale
Frequency of Alcohol Use
score on a scaleeCHECKUP TO GOControl
Baseline3.71 ± 1.942.84 ± 1.91
1 Month Follow-Up3.61 ± 1.892.72 ± 1.81
6 Month Follow-Up3.41 ± 1.802.62 ± 1.77
PrimaryBlood Alcohol Concentration

Blood alcohol concentration was calculated using the Widmark Formula (1932/1981); BAC = \[Alcohol consumed in grams / (Body weight in grams x r)\] x 100. In this formula, "r" is the gender constant. Minimum = 0; Maximum = none Sample score range: Minimum = 0; Maximum = .62 Higher scores are worse outcomes

Time frame:
Baseline, 1 month follow-up, and 6-month follow up
Reported as:
Mean · percentage of alcohol/100 ml of blood
Blood Alcohol Concentration
percentage of alcohol/100 ml of bloodeCHECKUP TO GOControl
Baseline.11 ± .16.06 ± .11
1 Month Follow-Up.07 ± .11.05 ± .11
6 Month Follow-Up.09 ± .15.07 ± .15
PrimaryHeavy Episodic Drinking

Heavy Episodic Drinking is defined as having 5 or more drinks in a row for males and 3 or more for females in a 2 hour period in the past month. The number of drinks was based on research by Donovan (2009) establishing cut-points for children and adolescents. Participants were asked: "Males: Think back over the last two weeks. How many times have you had 5 or more drinks in a two hour period?" "Females: Think back over the last two weeks. How many times have you had 3 or more drinks in a two hour period?" Minimum = 0; Maximum = none Sample score range: Minimum = 0; Maximum = .76 Higher scores are worse outcomes

Time frame:
Baseline, 1 month follow-up, and 6-month follow up
Reported as:
Mean · binge drinking events
Heavy Episodic Drinking
binge drinking eventseCHECKUP TO GOControl
Baseline.89 ± 1.32.61 ± 1.32
1 Month Follow-Up.73 ± 1.37.52 ± 1.14
6 Month Follow-Up.66 ± 1.23.49 ± 1.22
SecondaryAlcohol-Related Consequences

Rutgers Alcohol Problems Inventory Alcohol-related consequences were measured using the Rutgers Alcohol Problems Inventory. The Rutgers Alcohol Problems Inventory is a 23-item scale. Participants were asked "How many times have the following scenarios happened to you while you were consuming alcohol or as a result of your drinking in the past 30 days." Responses were measured on a 5-point scale ranging from 0 (never) to 4 (more than 10 times). A total consequence score is created by summing the 23 items. Minimum = 0; Maximum = 92 Sample score range: Minimum = 0; Maximum = 24 Higher scores are worse outcomes

Time frame:
Baseline and 6-month follow up
Reported as:
Mean · score on a scale
Alcohol-Related Consequences
score on a scaleeCHECKUP TO GOControl
Baseline3.62 ± 5.522.35 ± 4.89
6 Month Follow-Up2.70 ± 4.971.45 ± 2.80

Adverse events

Collected over 6 months. Non-serious events are listed at a 0% frequency threshold.

Adverse event summary by group
GroupDeathsSeriousOther
eCHECKUP TO GO0/174 (0%)0/174 (0%)0/174 (0%)
Control0/137 (0%)0/137 (0%)0/137 (0%)

Baseline characteristics

Age, Continuous
Age, Continuous(years)eCHECKUP TO GOControlTotal
Mean17.13 ± 0.4617.13 ± 0.4517.13 ± 0.45
Sex: Female, Male
Sex: Female, Male(Participants)eCHECKUP TO GOControlTotal
Female10073173
Male7464138
Race/Ethnicity, Customized
Race/Ethnicity, Customized(Participants)eCHECKUP TO GOControlTotal
White152112264
Hispanic/Latino6915
Asian7714
Black/African-American145
American Indian/Alaska Native224
Native Hawaiian/Pacific Islander202
Other437
Region of Enrollment
Region of Enrollment(participants)eCHECKUP TO GOControlTotal
United States174137311
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Study locations

1 site
  • Boise State University
    Boise, Idaho 83725, United States
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References and documents

Publications

  • Doumas DM, Esp S, Turrisi R, Bond L, Flay B. Efficacy of the eCHECKUP TO GO for High School Seniors: Sex Differences in Risk Factors, Protective Behavioral Strategies, and Alcohol Use. J Stud Alcohol Drugs. 2020 Mar;81(2):135-143. doi: 10.15288/jsad.2020.81.135. PubMed 32359042 ↗
  • Doumas DM, Esp S, Turrisi R, Bond L. A Randomized Controlled Trial of the eCHECKUP to GO for High School Seniors across the Academic Year. Subst Use Misuse. 2021;56(13):1923-1932. doi: 10.1080/10826084.2021.1958862. Epub 2021 Aug 4. PubMed 34347564 ↗

Study documents

PDFs hosted by the registry, ClinicalTrials.gov.

Individual participant data

Plan to share: No

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Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Sep 2018 to primary completion in Apr 2019, 6 months.

Results were first posted in Apr 2021, 2 years after primary completion.

Of 34 non-industry interventional studies with no phase under Underage Drinking, half reached primary completion within 24 months of starting (the median), counting those still running; a quarter within 13 and three quarters within 38. This study's 6 months is below that.

Counting every sponsor, half of 36 studies reached it within 24 months; a quarter within 12 and three quarters within 38.

How these figures are worked out, and which studies are left out of them.

Registered
Jul 30, 2018
First posted
Aug 3, 2018
StartActual
Sep 15, 2018
Primary completionActual
Apr 1, 2019
CompletionActual
Apr 1, 2019
Results first posted
Apr 1, 2021
Last update
Apr 1, 2021
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Apr 1, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03613818
Lead sponsor
Boise State University
Responsible party
Diana Doumas (Distinguished Professor, Boise State University) — Principal investigator
First posted
Aug 3, 2018
Start date
Sep 15, 2018
Primary completion
Apr 1, 2019
Completion
Apr 1, 2019
Results posted
Apr 1, 2021
Last update
Apr 1, 2021

Study contacts

Diana Doumas, PhD
principal investigator · Boise State Univeristy

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Mar 2021. You cannot join it, but the record below documents what was studied.

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